Trimethoprim

Name: Trimethoprim
Availability: trimethoprim-19072.html

Category:Active Pharmaceutical Ingredients > Sulfonamides
Product Name:Trimethoprim
CAS No.:38-70-5
Standard:USP, BP, EP
Price(USD):0.00
Company:Arshine Group Co.,Ltd.

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Basic Info

Grade: food grade, pharmaceutical grade, injection grade

Factory Location: Changsha Hu nan china china

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Packaging Information: 25KG/DRUM
Sample Provided: no

Payment Terms: T/T,L/C,DP,BANK CONTRACT

Hot sell Trimethoprim/TMP/38-70-5
1.Cas No.:38-70-5
2.Color:white
3.Standard:CP/USP
4.Packing:25kg/drum

Trimethoprim/TMP/CAS NO.:38-70-5

1.CAS NO.:38-70-5

2.Color:White powder

3.Standard:CP/USP

4.Packing:25kg/drum

Trimethoprim (INN) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections. It belongs to the class of chemotherapeutic agents known as dihydrofolate reductase inhibitors. Trimethoprim was formerly marketed by GlaxoSmithKline under trade names including Proloprim, Monotrim and Triprim; but these trade names have been licensed to various generic pharmaceutical manufacturers. In clinical use it is often abbreviated TRI or TMP; its common laboratory abbreviation is W.

Items	Standard	Results
Appearance	White or yellowish-white powder		White powder
Solubility	Very slightly soluble in water, slightly soluble in alcohol.		Very slightly soluble in water, slightly soluble in alcohol.
•Identification
A: Melting point	199-203		201.0-201.4
B: Specific absorbance	Max.287nm: 240-250		243
C: IR-spectrum	Complies with reference spectrum		Complies with reference spectrum
D: Chemical reaction	Green fluorescence at 365nm		Green fluorescence at 365nm
Appearance of solution	Not more intensely colored than Reference Solution BY7		Less intensely colored than reference solution BY7
Related substances
Method A by HPLC:
Impurity F	≤0.1%		0.05%
Any single impurity	≤0.1%		<0.1%
Total impurities	≤0.2%		<0.2%
Method B by HPLC:
Any single impurity	≤0.1%		<0.1%
Total impurities	≤0.2%		<0.2%
Heavy metals	≤20ppm		< 20ppm
Residual methanol	≤3000ppm		Not detected
Residual DMSO	≤5000ppm		Not detected
Residual acetic acid	≤5000ppm		Not detected
Impurity K(aniline) by GC	≤5ppm		Not detected
Loss on drying	≤0.5%		0.3%
Sulphated ash	≤0.1%		0.02%
Assay	98.5-101.0%		99.71%
Particle size	100% pass 300 mesh		100% pass 300 mesh

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Trimethoprim

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