Sulphadiazine

Product description
White or slightly yellow powder. mp 252-256°. Sparingly sol in water at 37°: 13 mg/100 ml at pH 5.5; 200 mg/100 ml at pH 7.5. Sparingly sol in alcohol, acetone. One gram dissolves in about 620 ml of human serum at 37°. Freely sol in dil mineral acids and in solns of potassium and sodium hydroxides and in ammonia water.
Application
Sulfadiazine is a short-acting sulfonamide. It is readily absorbed from the gastrointestinal tract and rapidly excreted by the kidney. As with other sulfonamides, there are few specific indications because of the wide range of safer and more effective alternative antibiotics. In addition, the emergence of resistance to the sulfonamides has rendered this drug class unsuitable for the treatment of many infections that responded to them in the past. Sulfadiazine is used primarily to treat urinary tract infections and as an adjunct for the treatment of a few parasitic diseases. Although sulfadiazine, like other sulfonamides, is fairly well tolerated, its use is associated with adverse effects. Hypersensitivity reactions and gastrointestinal upset are among the common side effects associated with sulfadiazine.It is also Used especially in the treatment of toxoplasmosis.
Package
25kg/drum
Specification