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β-nicotinamide mononucleotide, reduced form, disodium salt (NMNH) is a compound derived from β-nicotinamide mononucleotide (NMN). It is a reduced form of NMN and is commonly used as a research tool in the field of aging and metabolism.
Here are some key points about β-nicotinamide mononucleotide, reduced form, disodium salt (NMNH):
Chemical Structure: NMNH is derived from β-nicotinamide mononucleotide, which consists of a nicotinamide group linked to a ribose sugar and a phosphate group. The reduced form of NMN contains an additional hydrogen atom, resulting in the reduction of the nicotinamide group.
Biological Role: NMNH is believed to be involved in cellular energy metabolism and the regulation of various enzymatic reactions. It plays a role in the biosynthesis of nicotinamide adenine dinucleotide (NAD+), a coenzyme involved in numerous cellular processes, including energy production and DNA repair.
Applications: NMNH is primarily used as a research tool to investigate the role of NAD+ metabolism, sirtuins, and cellular energy homeostasis. It is studied for its potential benefits in age-related diseases, metabolic disorders, and mitochondrial dysfunction.
Stability and Storage: NMNH should be stored in a cool, dry place, protected from light and moisture. Proper storage conditions help maintain its stability and integrity.
Safety Considerations: NMNH is considered a relatively safe compound. However, as with any chemical substance, it is important to handle it with appropriate care, following good laboratory practices and wearing necessary personal protective equipment (PPE).