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Sera and Vaccines
Abemaciclib
Abemaciclib
Abemaciclib
Category:
Sera and Vaccines
CAS NO:
1231929-97-7
Standard:
ChP,USP,BP,EP,JP,In-house Standards,IP,Ph. Int,
Price Range:
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Main Sales Markets:
North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
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Quanzhou Fortune Biopharma Co.,Ltd.
Quanzhou Fortune Biopharma Co.,Ltd.
4
Years
Standard Member Standard Member
Show Room
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Basic Info
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Payment Method
L/C
Samples Provided
NO
Product Description

Abemaciclib is an oral cyclin-dependent kinase CDK4/6 inhibitor. In HR +, HER2-breast cancer cells, CDK4 and CDK6 promote phosphorylation of retinoblastoma protein (retinoblastomapChemicalbookrotein, Rb) and promote cell cycle progression and cell proliferation. Abemaciclib inhibits phosphorylation of Rb and blocks cell progression from the G1 phase of the cell cycle to the S phase, resulting in cell aging and apoptosis

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