HCGRP-(8-37) is a calcitonin gene-related peptide fragment with a sequence of 30 amino acids. HCGRP-(8-37) is the latest type of CGPR receptor antagonist with better affinity. In experiments, when HCGRP-(8-37) is used as a raw material, it can reduce the nerve pain induced by CGRP, is safe and has no side effects, and will not affect the normal physiological sensation and motor ability. Nowadays, CGRP8-37 has become one of the preferred raw materials for the specific treatment of neuropathic pain.