Category:
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CAS NO:
1642288-47-8
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Basic Info
Grade
Industrial Grade
Is Manufacturer
YES
Packaging Specification
Foil pouches
Payment Method
L/C
Samples Provided
YES
Product Description
Uses: Avacaitai (trade name Camzyos) is a small molecule cardiac myosin modulator for the treatment of adult patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM). oHCM is a single-gene cardiovascular disease caused by mutations in sarcomere proteins, particularly myosin, that can affect up to 1 in 200 people.
Mechanism of action: Mavacaitai reduces excessive cardiac contraction by reducing actin-myosin cross-bridge formation and inhibiting cardiac myosin ATPase activity. Both of these effects reduce contractility by modulating myosin function.
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