
Oncology treatment
Antimetabolic effect: By inhibiting dihydrofolate reductase, it prevents the reduction of dihydrofolate to tetrahydrofolate, which in turn interferes with the synthesis of DNA, RNA and protein, and inhibits the proliferation of tumor cells. It is often used in the treatment of acute leukemia, especially acute lymphoblastic leukemia, and also has certain curative effects on a variety of solid tumors such as chorioepithelial carcinoma, malignant molar pregnancy, breast cancer, lung cancer, head and neck tumors.
Combined chemotherapy: often used in combination with other anti-tumor drugs to form different chemotherapy regimens to improve the treatment effect, for example, in the treatment of osteosarcoma, it is often used in combination with doxorubicin, cisplatin, etc