
Hydroxyproplyl Beta Cyclodextrin (hydroxypropyl betadex) are purified polydisperse products resulting from the controlled reaction of propylene oxide and native beta-cyclodextrin. Hydroxypropyl beta-cyclodextrin is itself very soluble in water (greater than 500 mg/ml at room temperature compared to 18 mg/ml for beta-cyclodextrin), and is used for molecular encapsulation of a variety of sparingly water compounds to enhance the aqueous solubility of the encapsulated compound.
Other Name: Hydroxyproplyl Beta Cyclodextrin
CAS No.: 128446-35-5
Molecular Structure:
Standards: USP,CP2020
Grade: Oral or Injection
Storage:Preserved in well-closed containers
Shelf life : 2 years when properly stored.
Package:10kg/drum,20kg/drum.
Medical use of hydroxypropyl beta cyclodextrin
Hydroxypropyl beta cyclodextrin is considered an ideal pharmaceutical excipient and solubilizer in injections in pharmaceutical industry.Due to the low surface activity, low hemolytic activity and non-irritation to muscles.
Hydroxypropyl beta cyclodextrin works to solubilize water-insoluble drugs, enhance drug stability, improve drug bio-availability (improve efficacy or lower dosage of drugs), moderate and control drug release, and can also help to diminish the toxicity and side effects of drugs.
Further, hydroxypropyl beta cyclodextrin can be applied as a drug carrier in oral medications, injections, mucosal drug delivery system, transdermal drug delivery system, and targeted lipophilic drugs. Also, it is suitable as a protectant and stabilizer for proteins.