Category:
Biocatalysts
CAS NO:
599-79-1
Standard:
USP,BP,EP,
CAS 599-79-1 Sulfasalazine
Product name | Sulfasalazine |
CAS NO. | 599-79-1 |
Molecular Formula | C18H14N4O5S |
EINECS: | 209-974-3 |
MW | 398.39 |
Appearance | Dark yellow to brownish yellow powder |
Purity | 99% |
1. Sulfasalazine is an antiinflammatory agent that inhibits GSH-H-transferase. Sulfasalazine largely inhibits NF-κB activation and induces apoptosis in T-lymphocytes.
2. The compound also engages neutrophil apoptosis that can be abrogated by Tyr-K inhibitors, PKA inhibitors, or antioxidants. Sulfasalazine is shown to inhibit basic fibroblast growth factor-induced endothelial cell chemotaxis.