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ICR

cancer patients miss out on innovative new treatments

cancer NICE ICR

Institute for Cancer Research highlights missed opportunity for NICE to reform its cancer drug assessment processes.

February 7, 2022 by pharmatimes

Four-drug combo therapy shows benefit for newly-diagnosed myeloma patients

ICR carfilzomib lenalidomide KRdc myeloma

A four-drug combination therapy has shown significant benefit for patients with newly diagnosed myeloma, according to a new analysis led by researchers from The Institute of Cancer Research, London (ICR).

July 27, 2021 by pharmatimes

NICE’s decision not to approve Zytiga ‘frustrating’, says ICR

NICE ICR Zytiga Janssen

The National Institute of Health and Care Excellence (NICE) has decided not to recommend Janssen’s Zytiga after reviewing its previous decision to reject the drug in 2020.

July 16, 2021 by pharmatimes

Scientists identify link between genetic changes and rare childhood cancer rhabdomyosarcoma

ICR rhabdomyosarcoma TP53

Genetic changes may help to improve decision making for the treatment of the rare and aggressive form of childhood cancer rhabdomyosarcoma, according to a new international study led by researchers at the Institute of Cancer Research, London (ICR).

June 28, 2021 by pharmatimes

Researchers find CD38-targeting drugs may show promise against prostate cancer

ICR CD38 prostate cancer Darzalex

A new study suggests that drugs which target the CD38 protein molecule may show promise against prostate cancer by ‘reawakening’ the body’s immune response against this tumour type.

May 11, 2021 by pharmatimes

PARP inhibitors could exploit weaknesses in a range of cancers

PARP inhibitor ICR PBRM1 cancer

PARP inhibitors – a type of drug most commonly used to treat ovarian and breast cancers – could offer a new way of targeting a range of cancers with a particular gene defect in the PBRM1 gene, according to researchers.

April 26, 2021 by pharmatimes

Experts call for advanced radiotherapy funding to address COVID-19 cancer care backlog

ICR NHS radiotherapy

The Institute for Cancer Research, London (ICR) is urging the government to invest in advanced radiotherapy in a bid to address the backlog in NHS cancer care that has accumulated during the COVID-19 pandemic.

April 13, 2021 by pharmatimes

Cancer research in the UK faces ‘perfect storm’ of funding cuts

ICR cancer UK

The Institute of Cancer Research, London (ICR) has made an appeal to Prime Minister Boris Johnson after identifying a ‘perfect storm’ of funding cuts that could impact cancer research in the UK.

April 1, 2021 by pharmatimes

ICR’s ‘resistance-busting’ drug advances into Phase I trial

ICR EP0042 AML Aurora FLT3

The Institute of Cancer Research, London (ICR) has announced that its ‘resistance-busting’ drug EP0042 has entered a Phase I clinical trial in patients with cancers including acute myeloid leukaemia (AML).

March 19, 2021 by pharmatimes

Researchers identify existing drug’s potential for triple negative breast cancer

breast cancer TNBC ICR palbociclib CREBBP

Researchers at The Institute of Cancer Research, London (ICR) have identified an already approved breast cancer drug which could have promise in the treatment of triple negative breast cancer (TNBC).

January 29, 2021 by pharmatimes

ICR researchers identify potential new treatment for drug-resistant prostate cancer

ICR CCS1477 prostate cancer

Researchers from The Institute of Cancer Research, London (ICR) and the Royal Marsden NHS Foundation Trust have revealed the mechanism of action for a ‘promising’ new prostate cancer treatment.

January 13, 2021 by pharmatimes

ICR scientists create 3D protein structure for new therapy development

ICR 3D cancer

The UK Institute of Cancer Research, London (ICR) researchers have created a three-dimensional (3D) structure of a complex of molecules for new therapies.

December 21, 2020 by pharmaceutical-technology