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Inhibitor

Research Progress on the Structural Classification and Functional Applications of Lasso Peptides

Lasso peptides, a class of ribosomally synthesized and post-translationally modified peptides (RiPPs), are named for their characteristic interlocked lasso topology.

September 9, 2025 by Xiaonisha

Made-in-China New Drugs: Breaking Through the RMB 4-Billion Battlefield

new drugs market PD-1 inhibitor EGFR

In 2024, the "Billion-Yuan Club" of made-in-China first-in-class new drugs expanded to 16 members.

September 5, 2025 by lezhi

Research Progress in Drug Therapy for Systemic Lupus Erythematosus

SLE inflammatory immune inhibitor

Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by local or systemic inflammatory responses, with insidious onset and high potential morbidity and mortality rates.

September 3, 2025 by Xiaonisha

InnoCare Announces First Patient Dosed in the Registrational Trial of BCL2 Inhibitor Mesutoclax for Treatment of BTKi-treated MCL Patients in China

InnoCare inhibitor lymphoma biopharmaceutical company

InnoCare Pharma announced today that the first patient has been dosed in the registrational trial of B-cell lymphoma-2 (BCL2) inhibitor mesutoclax (ICP-248) for patients with BTK inhibitor treated mantle cell lymphoma (MCL) in China.

August 21, 2025 by PharmaSources

Ubiquitin-Proteasome Pathway and Progress in Drug Development

ubiquitin proteasome inhibitor

The ubiquitin-proteasome system serves as one of the crucial pathways for the "digestion" of intracellular proteins, regulating numerous vital biological processes such as cell proliferation, differentiation, apoptosis, and DNA repair.

August 13, 2025 by Xiaonisha

Advances in the Research of Targeting B Cells for the Treatment of Systemic Lupus Erythematosus

Targeting B Cells Systemic Lupus Erythematosus antibody inhibitor

Systemic Lupus Erythematosus (SLE) is a chronic, systemic autoimmune disease. The direct cause of SLE pathogenesis lies in the immune imbalance resulting from excessive B-cell activation.

July 25, 2025 by Xiaonisha

Can Myocarditis Lead to Heart Failure? Please Briefly Describe the Research Progress in Drug Treatment for Heart Failure

heart failure Myocardial inhibitor blocker

Recently, there have been online rumors about some recovered COVID-19 "positive" patients who started intense exercise shortly after recovery and then suddenly died due to myocarditis.

July 23, 2025 by Xiaomichong

XPOVIO® (selinexor) Approved for Commercialization in Indonesia, Further Expanding Antengene's Commercial Presence in APAC

XPO1 selinexor inhibitor

Antengene announced XPOVIO® (selinexor) was approved for commercialization in Indonesia. It's the first XPO1 inhibitor there. Since 2024, it has been approved in multiple APAC markets for various cancer indications.

March 5, 2025 by PR Newswire

Ascentage Pharma Announces a New Drug Application for Its Novel Bcl-2 Inhibitor Lisaftoclax Accepted and Recommended Priority Review Designation by CDE of China NMPA

Bcl-2 Inhibitor Ascentage Pharma Lisaftoclax

Ascentage Pharma announced that a NDA for its inhouse developed investigational novel Bcl-2 selective inhibitor, lisaftoclax (APG-2575)has been accepted and recommended the Priority Review designation CDE and NMPA.

November 22, 2024 by PR NEWSWIRE

InnoCare Announces First Subject Dosed in the Phase III Registrational Trial of TYK2 Inhibitor ICP-332 for the Treatment of Atopic Dermatitis in China

InnoCare TYK2 ICP-332 Inhibitor

InnoCare Announces First Subject Dosed in the Phase III Registrational Trial of TYK2 Inhibitor ICP-332 for the Treatment of Atopic Dermatitis in China

November 15, 2024 by PharmaSources

Has the Booming PD-1 Inhibitor Reached its Limit?

PD-1 Inhibitor Oncology

In the field of oncology, Opdivo and Keytruda, as core immunotherapy agents for PD-1 inhibitors, have delivered significant survival benefits to patients with a variety of cancers.

October 18, 2024 by Krebs Qin

InnoCare Announces Approval of Clinical Trial of BCL2 Inhibitor ICP-248 for Acute Myeloid Leukemia in China

Inhibitor Acute Myeloid Leukemia InnoCare

InnoCare Pharma announced today the approval of the Investigational New Drug (IND) to conduct the clinical trial of B-cell lymphoma-2 (BCL2) inhibitor ICP-248 in combination with azacitidine for acute myeloid leukemia (AML) in China.

September 19, 2024 by PharmaSources