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failure

ntra-Cellular Therapies Announces Progression to Higher Dose Cohort in ITI-214 Study

Intra-Cellular Therapies announced the successful completion of the second dose cohort (single dose of 30 mg administered orally) in Study ITI-214-104 (Study ‘104) ...

September 27, 2019 by americanpharmaceuticalreview

Dapagliflozin Lowers Risk for Worsening Heart Failure

DAPAGLIFLOZIN heart failure Diabetes cardiovascular

For patients with heart failure and reduced ejection fraction, dapagliflozin is associated with a lower risk for worsening heart failure or death from cardiovascular causes, regardless of the presence of type 2 diabetes ...

September 24, 2019 by drugs

SGLT2 Inhibitors Linked to Lower Risk for Heart Failure

inhibitors SGLT2 heart failure

Use of sodium glucose cotransporter 2 (SGLT2) inhibitors for type 2 diabetes is associated with a reduced risk for heart failure ...

September 23, 2019 by drugs

FDA grants Fast Track designation for Farxiga in heart failure

FDA Farxiga heart failure AstraZeneca

AstraZeneca announced that the US Food and Drug Administration (FDA) has granted Fast Track designation for the development of Farxiga (dapagliflozin) to reduce the risk of cardiovascular (CV) death...

September 18, 2019 by worldpharmanews

Fast Track designation given to heart failure treatment

treatment heart failure Farxiga

Farxiga (dapagliflozin) has been given Fast Track designation by the FDA to reduce the risk of cardiovascular death.

September 18, 2019 by europeanpharmaceuticalreview

Novartis’s heart failure drug Entresto presents mixed trial results

Novartis heart Entresto failure

Novartis has announced that its heart failure with reduced ejection fraction (HFrEF) drug Entresto (sacubitril/valsartan) has shown further efficacy in two Phase IV trials, PROVE-HF and EVALUATE-HF.

September 4, 2019 by pharmaceutical-technology

Poor HIV Control Ups Risk for Sudden Cardiac Death in Heart Failure

HIV heart failure SCD PHIV

Persons living with HIV (PHIV) who are hospitalized with heart failure are at an increased risk for subsequent sudden cardiac death (SCD)...

August 26, 2019 by drugs

Asian Study Finds Diabetes, Heart Failure a Dangerous Duo

Diabetes heart failure

Asian heart failure patients who also have type 2 diabetes can develop changes in the structure of their heart and are at increased risk for hospitalizations and premature death, a new study finds.

August 22, 2019 by drugs

Farxiga met primary endpoint in landmark Phase III DAPA-HF trial for the treatment of patients with heart failure

heart failure Farxiga DAPA-HF

AstraZeneca announced positive results from the landmark Phase III DAPA-HF trial which showed that Farxiga (dapagliflozin) met the primary composite endpoint with a statistically-significant and ...

August 21, 2019 by worldpharmanews

Excess Risk for Diabetes-Linked Heart Failure Greater in Women

heart failure women Diabetes

The excess risk for heart failure associated with diabetes is significantly greater in women than men, according to a meta-analysis published online in Diabetologia.

July 22, 2019 by drugs

Image-Based Model Predicts Radiation Tx Failure in Lung Cancer

Radiation Tx failure lung cancer

Image-Based Model Predicts Radiation Tx Failure in Lung Cancer.

July 4, 2019 by drugs

Microbes Tied to Pedicle Screw Loosening, Spinal Implant Failure

pedicle Spinal implant failure

Microbes Tied to Pedicle Screw Loosening, Spinal Implant Failure.

June 13, 2019 by drugs