Category:
Biocatalysts
CAS NO:
234656-20-2
Standard:
ChP,In-house Standards,
Liraglutide is a synthetic acylated human glucagon-like peptide-1 (GLP-1) analog, sharing over 97% sequence homology with native human GLP-1. Its molecular modifications primarily include two aspects: firstly, the substitution of lysine at position 34 with arginine, and secondly, the addition of a fatty acid side chain to the lysine at position 26. These structural alterations not only preserve and prolong the binding duration of the acylated product with proteins but also significantly address the inherent susceptibility of GLP-1 to degradation.