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AstraZeneca dumps Amgen-partnered drug after midphase fail
fiercebiotech
April 28, 2019
AstraZeneca has dropped (PDF) Amgen-partnered autoimmune drug prezalumab from its pipeline. The action follows the failure of the anti-B7RP1 antibody in a midphase Sjöogren’s syndrome trial.
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Crystallographic method accelerates drug development
europeanpharmaceuticalreview
April 28, 2019
Researchers have developed a novel method that speeds up the process of determining crystal structures of organic salts and significantly reduces the effort required to do so…
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Kineret reduces inflammation in stroke patients
europeanpharmaceuticalreview
April 28, 2019
An anti-inflammatory drug given to patients in the early stages of a stroke has been shown to reduce harmful inflammation…
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Combination immunotherapy improves survival in mouse models of mesothelioma
europeanpharmaceuticalreview
April 28, 2019
Combined treatment with two cancer immunotherapy drugs significantly prolonged survival in aggressive cancer malignant mesothelioma…
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Pharmaceutical company and its former executives charged for drug trafficking
europeanpharmaceuticalreview
April 28, 2019
Pharmaceutical company and its former executives charged for drug trafficking.
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Vial switch improves life-saving antiviral drug
cphi-online
April 26, 2019
Legacy Pharmaceuticals uses SCHOTT Type I Plus vials to overcome a leaching issue.
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FDA awards breakthrough status to La Jolla’s malaria therapy
europeanpharmaceuticalreview
April 26, 2019
FDA awards breakthrough status to La Jolla’s malaria therapy.
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IL-18 inhibitor drug holds great potential for inflammatory diseases
europeanpharmaceuticalreview
April 26, 2019
An international team of researchers has identified the key role that IL-18 protein plays in Still’s disease, making it a prime candidate for IL-18 inhibitor drug that is proving promising in current trials.
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Metformin may help with nicotine withdrawal
europeanpharmaceuticalreview
April 25, 2019
A drug that has helped millions of people around the world manage their diabetes may also help people ready to kick their nicotine habits…
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FDA accepts NDA for ALKS 5461 for major depressive disorder
europeanpharmaceuticalreview
April 25, 2019
The FDA has accepted for review the New Drug Application for ALKS 5461, a novel, once-daily, oral investigational medicine for the adjunctive treatment of major depressive disorder …