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Hangzhou Go Top Peptide Biotech Co.,Ltd.
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Gramicidin A is an antibiotic produced by Bacillus brevis. It is a linear pentadecapeptide with N-terminal formylation blocking an amino group and C-terminal with an aldehyde group. Gramicidin A can kill some microorganisms. Two short Gramicidin A molecules are inserted relatively from both sides of the membrane to form a transmembrane channel, which improves the permeability of the biofilm to certain monovalent cations and allows these substances to pass through the cell membrane along the concentration gradient, but short Gramicidin A is not significant Increase transportation speed. Studies have shown that Gramicidin A can inhibit the transcription of T7 bacteriophage DNA, inhibit membrane-bound epidermal adenylate phosphatase activity and inhibit the transformation of human lymphocytes in vitro. It can prolong the survival rate of heart transplantation in rat animal models. |
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Hangzhou Go Top Peptide Biotech Co.,Ltd.
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Gramicidin A is an antibiotic produced by short bacillus, for linear 15 peptide, formylation closed amino N end, C side is aldehyde group.
The gramicidin A can kill some bacteria.
Two gramicidin A molecule from relative insert can form film on both sides of the membrane channel, improve the biological membrane permeability of some of the monovalent cations, make these material suitable concentration gradient through the cell membrane, but gramicidin A does not significantly improve the transportation speed.
Research shows gramicidin can restrain T7 has A phage DNA transcription, inhibit membrane in combination with epidermal adenosine triphosphatase activity and lymphocyte transformation in vitro inhibitory people.
In the animal model of rats can prolong survival in heart transplant.
Storage: - 20 ℃ under freeze dry, avoid light preservation remark: used only for research, not for human body |
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Pharma Sources Insight January 2025
