10% Ceftiofur Injection

Saifeixin^®

Ceftiofur Injection

Long-term slow release, one shot last for seven days

No immunosuppression, can be used during viral vaccination

Good tolerance at the injection site

Features                                                                         

1. Long-term slow release, one shot last for seven days

The ceftiofur hydrochloride crystal combined with the new formulation process ensures the slow release of the active ingredient, and the blood concentration of the drug exceeds 90%. The minimum inhibitory concentration of respiratory pathogens is 168 hours (7 days).

1. Broad spectrum and efficient sterilization, less resistance

It has ideal effects on infections such as Pasteurella multocida, Pasteurella hemolyticus, Actinobacillus pleuropneumoniae, Haemophilus parasuis, Streptococcus, Staphylococcus, Escherichia coli and Salmonella.

Table 1 The minimum inhibitory concentration of Saifeixin in Shandong province

Note：MIC= minimum inhibitory concentration；MIC₅₀=Minimum inhibitory concentration of 50% bacteria inhibited；MIC₉₀=Minimum inhibitory concentration of 90% bacteria inhibited 90%

1. Safety
   1. The injection site is well tolerated;
   2. No adverse reactions have been observed in the injected pigs;
   3. No immunosuppression, can be used before and after inoculation of viral vaccine;
   4. After the bottle cap is opened, it is still valid when stored at low temperature for 12 weeks.

1. Bioequivalence

Table 1 Comparison of Saifin and similar preparations

Saifeixin's application, case on the farm                                                        

A pig farm in Shandong was weaned at 23 days of age. Piglets after weaning showed symptoms of porcine respiratory disease such as rough hair, cough, weight loss, and asthma. The incidence rate was 17%. In the test group, the piglets were injected with Saifeixin on the day of weaning, 0.3 ml per head. The results are as follows:

Table 2. Saifeixin test results

* Compared with the control, the average daily weight gain increased by 61 grams; the feed-to-weight ratio decreased by 0.27; the survival rate increased by 8%.

Safeixin’s usage                                                                 

1. One dose only: intramuscular injection at the neck, 5mg/kg body weight, or 1ml/20kg body weight.
2. No more than 2ml per injection site, more than 40kg pigs need more injection sites.

Safeixin medication procedure                                                                

1. For prevention, group health

According to the characteristics of the disease of the farm, it is usually 2 to 3 days before the onset of the disease.

1）7~10 days of age: intramuscular injection 0.2m l/head;

2）Nursery piglets: intramuscular injection 0.3ml/head on weaning day; or intramuscular injection 0.5ml/head 2 weeks after weaning;

3）On PRRS unstable farm: 1 to 2 weeks after weaning, injection of Saifeixin 1ml/20kg body weight.

1. For individual treatment

When the affected pig is diagnosed as a bacterial infection (or mixed infection) such as streptococcus suis, haemophilus parasuis, actinobacillus pleuropneumoniae or pasteurella multocida, it is immediately injected with 1 ml/20 kg body weight of Safeixin.

Others                                                                            

Traits: gray to gray yellow translucent suspension

Specification: 50ml: 5g

Withdrawal period: pig 4 days

Package: 50ml/bottle×20 bottles/box