ALLOPURINOL

Niksan Pharmaceutical is among world’s top most manufacturer, supplier, exporter and trader of the Allopurinol finished formulations moreover Allopurinol API. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of Allopurinol API and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical provides API and finished formulations of Allopurinol in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu Kashmir Etc.

Niksan pharmaceutical is also large exporter of the API and finished pharmaceutical products of Adapalene in many countries for years. The countries where we exporting are Nepal, Sri Lanka, Malaysia, Philippines, Kenya, Singapore, Hong Kong, S.A.R, China, Pakistan, United Arab Emirates, United States, Puerto Rico, Argentina, Egypt, Qatar, Taiwan, China, Algeria, Jordan, Uruguay, United Kingdom, Canada, Bangladesh, New Zealand, Saudi Arabia, Australia, Colombia, France, Vietnam, Ireland, Iraq, Thailand, South Africa, Ecuador, Serbia, Peru, Indonesia, Morocco, Israel, Greece, Romania, Mexico, Iran, Switzerland, Norway, Italy, Denmark, Belgium, South Korea, Netherlands, Venezuela, Hungary, Chile, Sweden, Germany, Ukraine, Spain, Poland, Brazil, Turkey, Russia, Japan and many more countries.

Allopurinol belongs to medicine class called xanthine oxidase inhibitors. Allopurinol used in the treatment of kidney stones. Allopurinol works by decreasing the production of uric acid in body and prevents the risk of kidney stone and gout. 

SYNONYMS: 4-HPP, Allopurinol, Allopurinolum, Alopurinol

IUPAC NAME: 1H-pyrazolo [3, 4-d] pyrimidin-4-ol

CAS NO: 315-30-0

FORMULA: C5H4N4O

MOLECULAR MASS: 136.112 g/mol

STORAGE CONDITIONS: Store in room temperature in dry place.

Do not put medicine in bathroom or kitchen.

Keep away from children and pets.

HOW TO USE: Take Allopurinol tablet once daily orally as directed by doctor. Take this medication with food to prevent the stomach upset. Take medication with full glass of water to get best effect.

HOW ALLOPURINOL WORKS: Allopurinol is xanthine oxidase inhibitor, Allopurinol acts by inhibiting the conversion of xanthine oxidase to xanthine to uric acid. Allopurinol inhibits the uric acid synthesis and prevents the risk of kidney stone and gout problem.

PHARMACOKINETICS: 90% of Allopurinol absorbed in GI track after the oral administration. It takes normally 1.5-4.5 hours to reach the peak plasma concentration.

Almost very small amount of Allopurinol binds with the plasma protein. The half-life of Allopurinol is between 1-2 hours. Allopurinol has rapid renal clearance and almost 80% of drug excreted by the urination.

SIDE EFFECTS: Allopurinol has side effects like nausea, stomach upset, stomach pain, vomiting, dizziness, drowsiness.  Tell your doctor if you see side effects like numbness, easy bleeding, kidney problem, dark urine, stomach/intestinal pain, eye pain, vision change, Other rare side effects like fever, swollen, rash, itching, dizziness, trouble in breathing.

PRECAUTIONS: IF you have medical history like liver disease, kidney problem, high blood pressure, fasting, diabetes problemtell your doctor about it. Before taking medication tell your doctor if you have allergies to Allopurinol medication.

This drug makes you drowsy so do not take any alcoholic beverage.

Do not drive or operate a vehicle after taking the medication.

CDSCO APPROVAL: Allopurinol S.R. caps approved by CDSCO in India in 22-11-2002,

Allopurinol tablet approved by CDSCO in India in March-1969

FORMULATIONS AVAILABLE IN MARKET:

Allopurinol 100mg tablet

Allopurinol 250mg tablet

Allopurinol 300mg tablet

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com 

https://cdscoonline.gov.in 

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult