ARTEMETHER

The Niksan Pharmaceutical is among world’s top most manufacturer, supplier, exporter and trader of the Artemetherfinished formulations moreover ArtemetherAPI. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of ArtemetherAPI and formulation situated in Ankleshwar, Gujarat, India.

Niksan Pharmaceutical provides API and finished formulations of Artemether in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu Kashmir Etc.

Niksan Pharmaceuticalis also large exporter of the API and finished pharmaceutical products of Artemether in many countries for years. The countries where we exporting are Cameroon, Niger, Mali, Somalia, Ghana, Malawi, Côte d’Ivoire, Burkina Faso, Nigeria, Tanzania, Angola, Sudan, Congo – Kinshasa, Uganda, Kenya, Zambia, Pakistan, Yemen, South Africa, Bolivia, Saudi Arabia, Colombia, Philippines, Australia, Netherlands, United Kingdom, France, Germany, United States, Canada, Brazil and many more countries.

Artemether belongs to the antimalarial class of medicine. Artemether used in the treatment of malaria caused by the plasmodium parasites. Artemether prevents the malaria by killing the parasite that causes the disease. Artemether give intra muscular injection.

SYNONYMS: Artemetero, Artemether, Artemetherum, Artemisininelactol methyl ether, Dihydroartemisinin methyl ether, Dihydroqinghaosu methyl ether, methyl-dihydroartemisinine

IUPAC NAME: (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclohexadecane

CAS NO: 71963-77-4

FORMULA: C16H26O5

MOLECULAR MASS: 298.37 g/mol

STORAGE CONDITION: Store in cool and dry place, away from direct heat and sun light.

Do not place in bathroom or kitchen.Keep away from children and pets.

HOW TO USE:Take this medication with or without food as prescribed by your doctor.

Take this medication twice a day for 3 days.Take medication with food or milk to prevent the stomach upset.Take Artemether injection intra muscularly.Take the medication regularly to get more benefits.

HOW ARTEMETHER WORKS: Artemether is peroxide containing anti-malarial medicine. Artemether cause degradation of haemoglobin by product and inhibits the O2 carrying capacity in the parasite.Thus Artemether act as anti-malarial medicine by killing and preventing the growth of plasmodium parasite.

PHARMACOKINETICS: Artemether absorbed in body after the oral and I.M. administration. The absorption of Artemether increases when taken with food. Almost 47%-76% of Artemether binds with the blood plasma protein.The half-lie of the medicine is between 1.9-2.2 hours.The Artemether eliminated through the hepatic pathway.

SIDE EFFECTS:The normal side effects like headache, sweating, nausea, vomiting, insomnia, stomach pain, cough, fever, chills, and dizziness.Contact your doctor if you see side effects like chest pain, dizziness, and fainting, irregular heartbeats.There are some rare allergic reactions like rash, swelling, itching.

PRECAUTIONS:Tell your doctor if you have any allergic reactions to Artemether.

Tell your doctor if you have any conditions like heart problem, stomach problem, liver problem, abdominal problem, kidney problem. Artemether causes heart related problem so kindly tell your doctor before using the Artemether medication.

CDSCO APPROVAL: Artemether + Lumefantrine approved by CDSCO in India in 26.12.2002,

Artemether 40mg/80mg + Lumefantrine 240mg/480mg tablets (additional Strength) approved by CDSCO in India in24.06.2008,

 Artemether + Lumefantrine Dispersible tablet (40/80mg + 240/480mg) (Additional Strength) approved by CDSCO in India in 05.08.2008,

 Artemether + Lumefantrine (80mg + 480mg/5ml) Dry syrup approved by CDSCO in India in 30.09.2008,

 Artemether injection approved by CDSCO in India in 02.08.1996            

FORMULATIONS AVAILABLE IN MARKET:

Artemether 40 MG tablets

Artemether 80 MG /1ML solution

Artemether 150 MG tablets

Artemether 80 MG+Lumefantrine 480 MG tablets

Artemether 20 MG+Lumefantrine 120 MG /ML solution

Artemether 20 MG+Lumefantrine 120 MG tablets

Artemether 40 MG+Lumefantrine 240 MG tablets

Artemether 80 MG+Lumefantrine 840 MG tablets

Artemether 60 MG+Lumefantrine 360 MG tablets

Artemether 40 MG+Lumefantrine 240 MG /5 ML solutions

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com