CAS 209216-23-9,Entecavir Monohydrate

Category:Active Pharmaceutical Ingredients > Antibiotics
Product Name:CAS 209216-23-9,Entecavir Monohydrate
CAS No.:209216-23-9
Standard:ChP
Price(USD):0.00
Company:TAIZHOU VOLSEN CHEMICAL CO.,LTD.

Basic Info
  • Factory Location: TZ

    Main Sales Markets: North America,Western Europe

  • Packaging Information: packaging : Length x Width x Height
    shipping_port :

  • Sample Provided: no

    We are enable to supply two type of entecavir: mirconized power/common power.

    Entecavir monohydrate(209216-23-9) is a nucleoside analog(more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process.

     

     

     

    Thera. Category: Adult chronic hepatitis B

    Cas No.:209216-23-9

    Synonym:entecavir hydrate;ENTECAVIR MONOHYDRATE;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate;Entecavir hydrate / 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate

    Molecular Formula:C12H17N5O4

     

    Molecular Weight:295.29448

    Pharmacopeia: In house Spec.

    Specifications:Available on request

    Packing:Export worthy packing

    Material Safety Data Sheet:Available on request

     

    Usage:This product is applicable to the treatment of adult chronic hepatitis B.

     

    CERTIFICATE OF ANALYSIS

    Product Name

    Entecavir Monohydrate

    Cas No.

    209216-23-9

    Producing Date

    2014-10-03

    Batch No.

    20141003

    Assaying Date

    2014-10-03

    Reporting Date

    2014-10-03

    Expiry Date

    2016-10

    Quantity

    50Gram

     

    Items

    Specifications

    Results

    Appearance

    White or off-white powder

    White powder

    Identification

    1)The IR absorption specturm of the sample must be same with entecavir

    2) RT of the sample should match that of standard assay preparation

     

    Comform

    Water

    5.8%~6.5%

    6.1%

    Optical rotation

    +24°~+28° (DMF:MOH=1:1 C=1%)

    +27.2°

    Residue on ignition

    ≤0.10%

    0.07%

    Heavy Metals

    ≤20ppm

    Conforms

    Related substances

    Total impurities

    ≤0.30%

    0.07%

    Single impurity

    ≤ 0.1%

    0.03%

     

     

    Residual solvents

    dichloromethane

    ≤600ppm

    100PPM

    methanol

    ≤1000ppm

    300PPM

    tetrahydrofuran

    ≤700ppm

    ND

    toluene

    ≤600ppm

    ND

    Assay (HPLC)

    99.8% ~102.0%(On anhydrous basis)

    ≥99.9%

    Particle size

    D90≤30um

    Conform

    Conclusion: The product corresponds to the requirements of in house standard.

     

     

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