CELECOXIB

Niksan Pharmaceutical is one of the leading Manufacturer, Exporter, Distributor, and Supplier of Celecoxibin Ankleshwar, Gujarat, India. To understand the largest accomplishment of clients, we present these products at very realistic price ranges. Niksan Pharmaceutical and Niksan group companies are nowadays one of the largest manufacturers and exporters of CelecoxibAPI and also finished formulations.

Niksan Pharmaceutical and Niksan group companies are the very well-known manufacturers, suppliers and distributors of Celecoxib products.

Niksan Pharmaceutical provides API and finished formulation of Celecoxib in many Indian states like Himachal Pradesh, Andhra Pradesh, Tamil Nadu, Telangana, Kerala, Karnataka, Gujarat, Jammu & Kashmir, Chandigarh, Punjab, Uttarakhand, Chhattisgarh, Haryana, Maharashtra, Odisha, Uttar Pradesh, Delhi, Rajasthan, Madhya Pradesh, West Bengal, Bihar, Assam and many other Indian states.

Niksan Pharmaceutical are manufacturing and exporting very large quantity of Celecoxibin countries like Zimbabwe, Peru, Philippines, Chile, Dominican Republic, Mexico, New Zealand, Guatemala, Honduras, Costa Rica,Sri Lanka, Ghana, Qatar, Ecuador, Vietnam, El Salvador, Colombia, Bolivia, Australia, 'Hong Kong, S.A.R., China', United Arab Emirates, Panama, Kenya, Singapore, Jordan, Canada, Malaysia, Iraq, Iran, United States, Nigeria, Pakistan, Romania, South Korea, Saudi Arabia, Germany, Netherlands, 'Taiwan, China', Spain, Thailand, Switzerland, South Africa, Portugal, Israel, Ireland, Algeria, Egypt, Belgium, Sweden, United Kingdom, Venezuela, Finland, Indonesia, Austria, Italy, China, Argentina, France,Brazil, Japan, Poland and many other countries.

Celecoxib belongs to the non-steroidal anti-inflammatory drug. Celecoxib generally used to treat the pain in the gout, rheumatoid arthritis, joint pain, osteoarthritis, inflammation in joints and kidney failure.

Celecoxib is cox- selective inhibitor.

SYNONYMS: Celecoxib, Célécoxib, Celecoxibum.

IUPAC NAME:4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide

CAS NO: 169590-42-5

FORMULA: C17H14F3N3O2S

MOLECULAR MASS: 381.37 g/mol

STORAGE CONDITION:Store in room temperature, away from heat and direct light.Do not store in kitchen or bathroom.Keep away from children and pet.

HOW TO USE:Take medication once or twice a day by orally with water.To avoid the chance of stomach pain or stomach upset take medication with food. Take your doctor’s advice if you have any confusion.

HOW CELECOXIB WORKS: Celecoxib give relief in, rheumatoid arthritis, joint pain, osteoarthritis, inflammation in joints, pain in the gout, by inhibiting the actions of COX-2 enzyme. Celecoxib also used to treat swelling in joints.

PHARMACOKINETICS OF CELECOXIB: Celecoxib rapidly absorbed in GI track after oral administration. It takes 1-2 hourstoreach the max plasma concentration.Almost 97% of Celecoxib binds with albumin in body.The half life of Celecoxib is 11 hours in the normal person.The primary elimination of Celecoxib done by hepatic metabolism, 57% of Celecoxib eliminated by faces and the remaining residues are excreted by urination.

SIDE EFFECTS OF CELECOXIB:Normally gas and stomach upset are the side effects seen in patients.The several side effects like headache, swelling of calf, kidney problems, problem in urination, yellow eyes, stomach pain.Get medical attention if you see side effects like black urine, swelling of limbs, stomach problem or yellowing of skin/eyes.There are some rare side effects like itching, swelling, dizziness, irritation, trouble in breathing also seen in patients.

PRECAUTIONS:Kindly tell you doctor if you have allergic reactions towards the Celecoxib medication. Do not take Celecoxib with the aspirin and other NSAID products.

Kindly avoid taking Celecoxib medicine if you have problem like liver problem, heart problem, kidney problem, stroke, blood pressure problem, ulcers.Take your doctor’s advice if you are pregnant or in lactation period.Use of alcohol or tobacco may cause stomach bleeding.

CDSCO APPROVAL: Celecoxib capsule approved by CDSCO in Indian in 22-02-2000, Celecoxib 100/200mg +Diacerein 50/50mg approved by CDSCO in Indian in 19.07.2010,

Celecoxib capsule approved by CDSCO in Indian in 15.02.2002,

Celecoxib Mouth Dissolving Tablet 50/100/200 mg approved by CDSCO in Indian in 25.02.2010,

Celecoxib injection approved by CDSCO in Indian in 2004-October, Celecoxib injection approved by CDSCO in Indian in 27.10.2004.

FORMULATION AVAILABLE IN MARKET:

Celecoxib 100mg +Diacerein 50mg capsules

Celecoxib 200mg +Diacerein 50mg capsules

Celecoxib 50 mg Mouth Dissolving Tablets

Celecoxib 100 mg Mouth Dissolving Tablets

Celecoxib 200 mg Mouth Dissolving Tablets

Celecoxib injection

Celecoxib 200mg capsules

Celecoxib 100mg capsules

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult