CLARITHROMYCIN

Niksan Pharmaceutical is the largest manufacturer and exporter of the Clarithromycinamong all over the world. Niksan Pharmaceutical is one of biggest the supplier, manufacturer, exporter and distributor of the ClarithromycinAPI and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical provides API and finished formulations of Clarithromycin in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu, Madhya Pradesh, Uttar Pradesh, Kashmir Etc.

Niksan Pharmaceuticalis also large exporter of the API and finished pharmaceutical products of Clarithromycin in many countries for years. The countries where we exporting are Ireland, United Kingdom, Ghana, Philippines, Singapore, Jamaica, Pakistan, Kenya, Canada, Qatar, Jordan, Sri Lanka, Austria, Nigeria, Tanzania, Vietnam, Australia, United Arab Emirates, Oman, Kuwait , 'Hong Kong, S.A.R., China', Lebanon, Germany, Lithuania, United States, Iraq, Latvia, Malaysia, Saudi Arabia, Switzerland, Denmark, South Africa, Thailand, Bangladesh, New Zealand, 'Taiwan, China', Egypt, Greece, South Korea, Hungary, Israel, Bulgaria, Norway, Czechia, Iran, Indonesia, Belgium, China, Sweden, Netherlands, Poland, Spain, Mexico, Turkey, France, Japan, Italy, Brazil and many more countries.

Clarithromycinis simply given as an antibacterial drug. Clarithromycin belongs to the macrolide antibiotic which is used to prevent the growth of bacteria in infected place.

Clarithromycinis also given in the combinations to treat the GI ulcers and bacterial infections.

SYNONYMS OF CLARITHROMYCIN: 6-O-methyl erythromycin, 6-O-methylerythromycin A, Clarithromycin, Clarithromycina, Clarithromycine, Clarithromycinum, Claritromicina.

IUPAC NAME: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione

CAS NO: 81103-11-9

FORMULA:C38H69NO13

MOLECULAR MASS: 747.95 g/mol

STORAGE CONDITIONS: Store in cool dry place away from direct sun light.Do not keep container in humid or moist place like bathroom.Keep away from children and pets.

HOW TO USE:Take medicine by mouth with or without food.Take medicine 2 times per day. If you feel stomach upset take medicine with food or milk.Take medication regularly to get more benefits.

HOW CLARITHROMYCIN WORKS:Clarithromycin simply stops the growth of bacteria and by that it is used in the treatment of bacterial infections, pneumonia, skin infections, stomach ulcers etc.

PHARMACOKINETICS: Clarithromycin kills much type of gram positive and gram negative bacteria by destroying their cell walls. Clarithromycin is well absorbed in body and also it is acid stableand binds with almost 70% plasma protein.The half-life of Clarithromycin is between 3-4 hours.The elimination of Clarithromycin is done by 20% by urine.

SIDE EFFECTS OF CLARITHROMYCIN:The normal side effects like vomiting, nausea, headache, and change in taste are common.If you see side effects like hearing loss, muscle weakness, stomach pain, eye pain, speaking problem, eye problem, tell you doctor about it.The medicine rarely causes intestinal problems when taken for long time.

PRECAUTIONS:Tell your doctor if you have allergic reactions to the Clarithromycin or inactive ingredients.Clarithromycin can cause problem related to heart like hear beat problem, irregular heartbeats, and other problems like dizziness fainting.Kindly take your doctor’s advice if you see such kind of problem.

CDSCO APPROVAL:Combipack of Omeprazole + clarithromycin + amoxicillin tablet approved by CDSCO in Indian in 01.10.2002,

Clarithromycin tablets tablet approved by CDSCO in Indian in 22.03.1995,

Combipack tablet approved by CDSCO in Indian in   09.09.1997,

Clarithromycin 1% gel approved by CDSCO in Indian in   12.06.2002,

Clarithromycin M.R tabs approved by CDSCO in Indian in    16.10.2001

FORMULATIONS AVAILABLE IN MARKET:

Clarithromycin 1%w/w cream

Clarithromycin 1%w/v gel

Clarithromycin250mg tablets

Clarithromycin 500mg tablets

Clarithromycin 125mg tablets

Clarithromycin 125mg/5ml solution

Clarithromycin 250mg/5ml solution

Omeprazole + Clarithromycin + amoxicillin tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult