ERYTHROMYCIN

Niksan Pharmaceutical is world’s leading manufacturer, trader, exporter and supplier of the Erythromycin API and Erythromycin formulations. Niksan Pharmaceutical manufactures large quantity of Erythromycin API and finished products in Ankleshwar, Gujarat, India. Niksan Pharmaceutical and Niksan group companies are the largest manufacturers and suppliers of Erythromycin products.

Niksan Pharmaceutical exporting very big quantity of the fines quality products of Erythromycin in all over world for many years in countries like Zambia, Zimbabwe, Nigeria, Philippines, Tanzania, Kenya, Ghana, Uganda, New Zealand, United Kingdom, Sri Lanka, United States, Australia, Malaysia, Singapore, Ireland, Lebanon, Vietnam, Pakistan, Canada Germany, United Arab Emirates, Puerto Rico, Jordan , South Africa, Iraq, Austria, 'Hong Kong, S.A.R., China', Thailand , Bangladesh, Indonesia, 'Taiwan, China', Saudi Arabia, Egypt, Denmark, Israel, Norway, Switzerland, South Korea , Greece, China, Iran, Hungary, Sweden , Belgium, Netherlands, Poland, Spain, France, Mexico, Turkey, Japan and many more countries.

Niksan Pharmaceutical provides best quality product of Erythromycin in all states of India like Kerala, Punjab, Rajasthan, Telangana, Bihar, Karnataka, Jammu and Kashmir, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Delhi, Tamil Nadu, Odisha, Madhya Pradesh, Andhra Pradesh, Haryana  and many other states.

Erythromycin is one type on anti-bacterial medicine which is use in the treatment of several bacterial infections. Erythromycin belongs to the macrolide antibiotics. Erythromycin inhibits the bacterial infection by inhibiting the growth of bacteria.

SYNONYMS: Abomacetin, Eritromicina, Erythromycin, Erythromycin A, Erythromycin C, érythromycine, Erythromycinum.

IUPAC NAME:(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione

CAS NO: 114-07-8

FORMULA:C37H67NO13

MOLECULAR MASS: 733.93 g/mol

STORAGE OF ERYTHROMYCIN:Store in cool and dry place, keep away from direct light and heat.Do not put medication in humid place like bathroom or kitchen.Keep away from pets.

HOW TO USE:Erythromycin normally taken orally with or without food.If you feel nausea or vomiting take medicine with food of milk.Erythromycin has bitter taste so do not chew or crush tablet.Take your doctor’s advice if you have any confusion.

HOW ERYTHROMYCIN WORKS:Erythromycin works as an anti-bacterial agent. Erythromycin prevents the bacterial infections by killing the bacteria and also prevents the further growth of bacteria.Erythromycin also use in the treatment of respiratory, stomach or intestinal infection by inhibiting the bacterial growth.

PHARMACOKINETICS:Erythromycin binds with 23s ribosomal RNA and by this v inhibits the protein synthesis which is required for bacteria to build their cell wall, by inhibiting the protein synthesis bacteria will unable to grow cell wall and by this process the bacterial growth can be inhibited.Erythromycin rapidly absorbed in the body after oral administration. Erythromycin takes 1.2hours to reach the peak plasma concentration.Erythromycin binds with almost 80-90% of plasma proteins.The half-life of the medication is 2.4-3.1 hrs. And Erythromycin eliminated by bile.

SIDE EFFECTS:The common side effects of Erythromycin are nausea, vomiting, loss of appetite, stomach/abdominal pain, cramping is seen in the patients.Take medical attention if you see some side effects like dark urine, yellow eyes, stomach pain, liver disease, muscle weakness, tiredness, blurred vision, problem in speaking. Erythromycin also causes some intestinal problems like abdominal pain, blood or mucus in your stool, cramping in intestines.

PRECAUTIONS: Tell your doctor if you are allergic to Erythromycin.Tell your doctor if you are taking any other medication, and also about your past medical history like if you have liver, kidney or heart related problem.Erythromycin effects on the heart so if you see symptoms like slow/irregular heartbeats, problem in breathing or chest pain take immediate medical attention.

CDSCO APPROVAL: Erythromycin Propionate + Benzyl alcohol + Lidocane approved by CDSCO in Indian in March-1974.

Isotretinoin 0.05% + Erythromycin 2% gel approved by CDSCO in Indian in   08.06.2007,

Erythromycin approved by CDSCO in Indian in 07.02.2000

FORMULATIONS AVAILABLE IN MARKKET:

Erythromycin 3% w/w cream

Erythromycin 2% w/v ointment

Erythromycin 4% w/v ointment

Erythromycin 2% w/w cream

Erythromycin 250mg tablets

Erythromycin 500mg tablets

Erythromycin 100mg/ml solution

Erythromycin 125mg tablets

Erythromycin 100mg tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult