FEXOFENADINE

Niksan Pharmaceutical is world’s leading manufacturer, trader, exporter and supplier of the FexofenadineAPI and Fexofenadine formulations. Niksan Pharmaceutical manufactures large quantity of Fexofenadine API and finished products in Ankleshwar, Gujarat, India. Niksan Pharmaceutical and Niksan group companies are the largest manufacturers and supplier of Fexofenadine products.

Niksan Pharmaceutical exporting very big quantity of the fines quality products of Fexofenadine in all over world for many years  in a countries like Maldives, Nepal, Bangladesh, Sri Lanka, United Kingdom, Puerto Rico, United States, Australia, Vietnam, Singapore, Qatar, Pakistan, United Arab Emirates, Hong Kong,S.A.R.,China, Taiwan,China, Netherlands, Thailand, Kenya, Malaysia, Jordan, Ireland, New Zealand, South Africa, Iraq, Saudi Arabia, Israel, Nigeria, Philippines, Iran,Egypt, Indonesia, Switzerland, Canada, South Korea, France, Belgium, Colombia, Germany, Mexico, Poland, Japan, Spain, Brazil, Turkey, Italy and many more countries.

Niksan Pharmaceutical provides API and finished formulations of Fexofenadinein all over Indian states LikeJammu Kashmir,  Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar Etc.

Fexofenadine belongs to the drug class called antihistamines. Fexofenadine used in the allergic treatment like watery eye, swollen skin, rash, itching or irritation. Fexofenadine prevents the allergic reaction by blocking the effects of histamine.

SYNONYMS OF FEXOFENADINE: Carboxyterfenadine, Fexofenadina, Fexofenadine, Terfenadine acid metabolite, Terfenadine carboxylate, Terfenadine-COOH.

IUPAC NAME:2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl) piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid

CAS NO:83799-24-0

FORMULA:C32H39NO4

MOLECULAR MASS: 501.68 g/mol g·mol −1

STORAGE CONDITIONS:Store in cool and dry place, away from the direct heat and light.Do not put Fexofenadine medication in bathroom and humid place.Keep away from children and pets.

HOW TO USE:Take medication directly by mouth 2 times per day after 12 hours.If you use oral solution, kindly shake well before use.Take your doctor’s advice before using the medication.

HOW FEXOFENADINE WORKS:Fexofenadine blocks the effects of histamine which cause allergic reaction. By blocking the histamine effects Fexofenadine prevents the allergic reactions like skin rash, watery eyes, itching and irritation which is caused by the other medication.

PHARMACOKINETICS OF FEXOFENADINE: Fexofenadine absorbs rapidly after the oral administration. Fexofenadine take 1-3 hours to reach the peak plasma concentration.Almost 60-70% of Fexofenadine binds with the blood plasma protein.The half-life of Fexofenadine is between 11-15 hours. Almost 80% of Fexofenadine eliminated by feces and only 11% residues eliminated through urination.

SIDE EFFECTS OF FEXOFENADINE:The common side effects like ever, cold and stomach upset seen some time.Some rare side effects like allergic reactions like rash, itching, swelling of face, tongue, dizziness and trouble in breathing are caused by Fexofenadine medication.

PRECAUTION:Kindly tell your doctor if you have diabetes, PKU and other blood sugar related problem.Tell your doctor if you are allergic to the Fexofenadine medication.

Tell your doctor if are already taking other medication.If you have kidney disease or liver disease kindly tell your doctor.

CDSCO APPROVAL: Fexofenadine 120mg + Montelukast 10mg tablet approved by CDSCO in India in 31.08.2010,

Fexofenadine HCl tablets approved by CDSCO in India in 16.09.1998,

Fexofenadine suspension (30mg/5ml) approved by CDSCO in India in 19.01.2007,

Fexofenadine + pseudo ephedrine ER Tabs approved by CDSCO in India in 17.09.1999,

Fexofenadine HCl approved by CDSCO in India in 01.11.2000,

Fexofenadine HCl suspension approved by CDSCO in India in 27.08.2001,

Fexofenadine 120mg + Montelukast 10mg Chewable tablet approved by CDSCO in India in 07.07.2011

FORMULATION AVAILABLE IN MARKET:

Fexofenadine 120mg + Montelukast 10mg tablets

Fexofenadine HCl tablets

Fexofenadine suspension 30mg/5ml

Fexofenadine + pseudo ephedrine ER Tablets

Fexofenadine HCl suspension

Fexofenadine 120mg + Montelukast 10mg Chewable tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult