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Email ：PharmaSources@imsinoexpo.com
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Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa
Sample Provided: no
【 Main ingredient 】 Flufenicol
[Sex] This product is colorless or light yellow clarified liquid.
[Pharmacological action] Pharmacodynamics Flfenicol is a broad spectrum antibiotic in the amidol class, a bacteriosuppressor, which acts by binding with the ribosome 50S subunit to inhibit the synthesis of bacterial proteins. It has strong antibacterial activity against a variety of gram-positive and Gram-negative bacteria. Pasteurella hemolyticus, Pasteurella multocida and actinobacillus pleuropneumoniae were highly sensitive to flufenicol. In vitro, the antimicrobial activity of flufenicol against many microorganisms is similar or stronger than that of sulfenicol, and some bacteria that are resistant to aminools due to acetylation, such as Escherichia coli and Klebsiella pneumoniae, may still be sensitive to flufenicol.
It is mainly used for the bacterial diseases of pigs, chickens and fish caused by sensitive bacteria, such as Pasteurella hemolyticus, Pasteurella multocida and actinobacillus pleuropneumoniae caused by bovine and pig respiratory diseases. Typhoid fever and paratyphoid fever caused by salmonella, chicken cholera, chicken white dysentery, escherichia coli, etc. Fish Pasteurella, Vibrio, staphylococcus aureus, hydroomonas, enteritis and other bacteria caused by fish bacterial septicemia, enteritis, erythroderma and so on.
Pharmacokinetics The absorption of flufenicol is rapid, and the therapeutic concentration can be reached in the blood after about 1 hour, and the peak blood concentration can be reached in 1 to 3 hours. The bioavailability is over 80%. Flufenicol is widely distributed in animals and can cross the blood-brain barrier. It is mainly excreted in the urine in its original form, and a small amount is excreted in the stool.
【 Drug interaction 】
(1) Macrolides and Lincoamines have the same target as this product, they are bound to the 50S subunit of bacterial ribosomes, and can produce antagonistic effects when combined.
(2) may antagonize the bactericidal activity of penicillins or aminoglycosides, but has not been demonstrated in animals.
【 Action and use 】 Amidol antibiotics. For Pasteurella and Escherichia coli infections.
[Usage and dosage] by this product. Mix: 1~1.5ml of chicken per 1L of water for 5 days.
[Adverse reactions] This product has a certain immunosuppressive effect when used at higher than the recommended dose.
【 Note 】
(1) Chickens that lay eggs for human consumption shall not be used during the laying period.
(2) Breeding chickens should be used with caution. It is toxic to embryos and should be used with caution during pregnancy and lactation.
(3) Animals with severe immune function impairment or vaccination period are prohibited.
(4) Animals with renal insufficiency should be appropriately reduced or extended administration interval time.
【 Drug withdrawal period 】 Chicken 5 days.
10 percent
[Packing] 500ml/ bottle, 32 bottles/box
【 Storage 】 Dark, sealed storage.
[Approval number] Veterinary Medicine 170612111
【 Manufacturer 】 Wuhan Liyao Pharmaceutical Co., LTD. (Sino-Foreign joint venture)
Audited Supplier
Pharma Sources Insight JANUARY 2024
