Hualan-IVIG

[Composition]

Active ingredients: human immunoglobulin, mainly IgG

Excipients: Polysorbate 80, maltose, WFI

[Characters]

It is a colorless or light yellow clear liquid. Opalescence may occur but without turbidity.

[Indications]

1.Primary immunoglobulin deficiency diseases, such as X-linked hypoimmunoglobulinemia, common variable immunodeficiency disease (CVID), IgG subclass deficiency, etc.

2. Secondary immunoglobulin deficiency diseases, such as severe infections, neonatal septicaemia, etc.

3.Autoimmune diseases (AID), such as primary thrombocytopenic purpura, Kawasaki disease (KD), etc.

[Strength]

2.5g/vial (5% 50ml)

[Administration and Dosage]

Administration: Intravenous infusion or intravenous infusion after being diluted 1-2 times with 5% glucose solution. The beginning dripping speed shall be 1.0ml/min (approximately 20 drops/min). If no adverse reactions occur within the first 15 minutes, speed up gradually; but the maximum speed shall not exceed 3.0ml/min (approximately 60 drops/min).

Dosage: in the direction of the physician.

Recommended dosage:

1. Primary immunoglobulin deficiency or low diseases: Initial dose: 400 mg/kg BW. Maintenance dose: 200-400 mg/kg BW; the administration interval shall depend on the serum IgG level and the conditions of patients, generally once a month.

2. Primary thrombocytopenic purpura: 400mg/kg BW every day for consecutive 5 days. Maintenance dose: 400mg/kg BW; the administration interval shall depend on the platelet count and the conditions of patients, generally once a week.

3. Severe infections: 200-300mg/kg BW every day for consecutive 2-3 days.

4. Kawasaki disease: The product shall be used within 10 days after the disease attack. The dosage for children is 2.0g/kg BW and it shall be administered in one shot.