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Sodium hyaluronate (pharmaceutical grade) HA is major components in human stromal cells,vitreous,synovial fluid and other connectivetissue in the body HA plays an important role in retaining water, maintain extracellular space,adjusting osmotic pressure, lubrcating and improving cells reparation.Hyaluronic acid molecule contains a large number of hydroxyl groups, in can form hydrogen bonds intra-molecular and inter-molecular in aqueous solution, which offers a powerful water retention function to combine more than 400 times volumn water. At relativelyhigher concentration,its aqueous solution has remarkable viscoelasticity due to the complicated third-class reticular structure formed through the interaction of molecule.As a major components of intercellular substance.HA directly takes part in electrolyte alternate control between cells and exerts the function of message filter of physics and molecule.High molecular HA can restrain the movement,multiplication and phagocytosis of cells while low molecular HA plays a role of stimulation. HA has unique physicochemical properties functions.It has been widely applied in the pharmaceutical industry.HA can be used as viscoelastic material in intraocular lens implantation and as fillers in articular surgery against osteoarthritis ,rheumatoid arthritis etc. It is also used as medium in eye drops extensively.Furthermore, HA is helpful in preventing post-surgery conglutination and improving wound healing.The compound as a result of its reaction to other medicine may play a role of sustained release,thus achieving the purpose of targeted and timed release. hyaluronic acid is the same from whatever source it is isolated, and it is so common in the body that it can be used as a hypoallergenic surgical material for reconstructing and building up tissues that are lost. So hyaluronic acid has become a widely used substance among plastic and reconstructive surgeons. With the development of medical science, HA will become more and more useful.l in the field of medicine.