METHYLPREDNISOLONE

Niksan pharmaceutical is one of the leading manufacturer, supplier and exporter of the Methylprednisolone. The best anti product manufactured by Niksan Pharmaceutical is Methylprednisolone.  We manufacture, supply and export best quality product of Methylprednisolone API along with Methylprednisolone formulations.

Niksan Pharmaceutical is also manufacture and exports large quantity of Methylprednisolone products in whole globe since many years in countries like Indonesia, Puerto Rico, United States, Sri Lanka, Philippines, 'Taiwan, China', United Arab Emirates, Saudi Arabia, Australia, Vietnam Bangladesh, South Korea, Singapore, New Zealand, Canada, Malaysia, Belgium, Pakistan, Ireland, Iran, United Kingdom, Greece, Thailand, France, Egypt, Netherlands, Turkey, Mexico, Germany, Italy and many more countries.

Niksan Pharmaceutical provides best quality product of Methylprednisolone in all states of India like Kerala, Punjab, Rajasthan, Telangana, Uttar Pradesh, Gujarat, Delhi, Tamil Nadu, Bihar, Karnataka, Jammu and Kashmir, Maharashtra, West Bengal, Odisha, Madhya Pradesh, Andhra Pradesh, Haryana  and many other states.

Methylprednisolone is one type of anti-inflammatory drug. Methylprednisolone belongs to the medicine class called corticosteroids. Methylprednisolone used in the condition like cancer, blood disorders, arthritis, eye infections and many more.

SYNONYMS: Methylprednisolon, Methylprednisolone, Methylprednisolonum, Metilprednisolona

IUPAC NAME: (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one

CAS NO: 83-43-2

FORMULA: C22H30O5

MOLECULAR WEIGHT: 374.47 g·mol−1

STORAGE CONDITIONS: Store in cool and dry place. Keep away from direct hear or sin light. Do not put medicine in bathroom or kitchen. Keep away from children.

HOW TO USE: Take medication by mouth with or without food. Take medication one time per day. To get most benefits take medication regularly.

HOW METHYLPREDNISOLONE WORKS: Methylprednisolone works by inhibiting the vasodilation of capillaries, and also decrease the migration of leukocytes to the site of inflammation. And by this activity Methylprednisolone gives anti-inflammatory effects.

PHARMACOKINETICS: Methylprednisolone absorbed rapidly after the oral administration. Methylprednisolone gives about 89-90% of bioavaibility. 75-78% of Methylprednisolone binds with the plasma protein. The half-life of Methylprednisolone is 2.3hours. The elimination of Methylprednisolone is done by urination.

SIDE EFFECTS: The common side effects of Methylprednisolone are nausea, vomiting, trouble in sleeping; hear burn headache, sweating and loss of appetite. Methylprednisolone cause blood pressure rise that can worsen the diabetes.

Methylprednisolone increase thirst and urination. Tell your doctor if you see side effect like fever, sore throat, cough, chills.

PRECAUTIONS: Tell your doctor if you have any allergic reaction to the Methylprednisolone. Tell your doctor if you have problem like blood clots, bitter bones, eye disease, high blood pressure, stomach problems, abdominal problem. This drug makes you dizzy so do not do any activity like driving, exercise, or operating machineries.

CDSCO APPROVAL: Clotrimazole (10mg) + Methylprednisolone Acrponate 1mg/gm of cream approved by CDSCO in India in 12.07.2007,

Mupirocin (2%) + Methylprednisolone Acrponate (0.1%) Cream approved by CDSCO in India in 31.10.2007,

 Methylprednisolone aceponate-1mg + Mupirocin-20mg cream approved by CDSCO in India in 21.11.2007,

Methylprednisolone approved by CDSCO in India in 1978-March,

 Methylprednisolone acetate approved by CDSCO in India in 1962- November,

 Methylprednisolone Tablet 8mg approved by CDSCO in India in 01.09.2009,

Methylprednisolone Acrponate topical solution 0.1% approved by CDSCO in India in 09.04.2007

FORMULATION AVAILABLE IN MARKET:

Methylprednisolone 4mg tablets

Methylprednisolone 8mg tablets

Methylprednisolone 1mg tablets

Methylprednisolone 40mg/ml solution

Methylprednisolone 16 mg tablets

Methylprednisolone 2mg tablets

Methylprednisolone 10 mg tablets

Methylprednisolone 24mg tablets

Methylprednisolone 125mg tablets

Methylprednisolone 500mg tablets

Methylprednisolone 250mg tablets

Methylprednisolone 0.1%w/w cream

Methylprednisolone aceponate-1mg + Mupirocin-20mg tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult