Microlex® C.PVD S600

Properties:

. Drug Solublization, Tablet Binding, Tablet Film Coating

. Provides a matrix to solubilize poorly soluble drugs in melt-extruded or spray-dried solid dispersions

. Applied in a wide variety of dosage forms including oral solid, liquid, and topical formulations

. A linear random water-soluble copolymer of N-vinylpyrrolidone and vinyl acetate that combines a

unique set of properties for application in a wide variety of dosage forms

. A key ingredient in high-solids film coating formulations

. Applications:

. Low Tg for ease of processing in hot-melt extrusion and spray drying

. Compatible with other ingredients to allow optimization of solid dispersion formulations for stability and delivery

. Film former for topical applications

. High bonding capabilities in granulations

. Nonionic to minimize API interactions

. Increases tablet strength and reduces friability due to high compressibility and excellent adhesive properties

. Physiologically inert for good safety profile

. Solubility in aqueous and polar organic solvents adds processing flexibility

. Improved film adhesion

. Increased processing efficiencies