N6-Bz-5'-O-DMT-2'-O-TBDMS-A-CE

99%Min N6-Bz-5'-O-DMT-2'-O-TBDMS-A-CE RNA Phosphoramidites Synthesis CAS 104992-55-4

Product name: N6-Bz-5'-O-DMT-2'-O-TBDMS-A-CE

Purity: 99%min

CAS No.: 104992-55-4

RNA phosphoramidites, along with RNA CPG, and analogous to DNA synthesis support the synthesis of sequence-specific RNA oligonucleotides for RNA interference (RNAi) and can be used in target validation and other drug development techniques. Modern phosphoramidite-mediated synthesis has enabled routine high-yielding preparations of RNA oligonucleotides. High-quality RNA phosphoramidites are key to low failure rates, the high biological activity of synthesis products, and cost-effectiveness.

Key Features

Industry-standard 2′O-TBDMS protective group
Consistent lot-to-lot purity and performance
Compatible with deprotection methods based on methylamine or AMA
Standard RNA phosphoramidites provide excellent coupling results when used with ETT or BTT as an activator; best results are obtained with activator 42
Capping with standard acetic anhydride capping reagent rather than with fast Deprotection Cap A
Manufactured under a certified ISO 9001 quality system
DMT-2′O-TBDMS-rA(bz) Phosphoramidite is configured for ÄKTA and OligoPilot Synthesizers.