ROSUVASTATIN

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:ROSUVASTATIN
CAS No.:287714-41-4
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Company:NIKSAN PHARMACEUTICAL

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: ANKLESHWAR , GUJARAT , INDIA

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa

  • Monthly Production Capacity: 500 KG

    Packaging Information: HDPE DRUM WITH LDPE INNER LINNR

  • Delivery Lead Time: IMMEDIATE

    Sample Provided: yes

    Payment Terms: L/C

    Niksan Pharmaceutical is among world’s top most manufacturers, supplier, exporter and trader of the Rosuvastatin finished formulations moreover RosuvastatinAPI. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of RosuvastatinAPI and formulation situated in Ankleshwar, Gujarat, India.

     

    Niksan Pharmaceutical provides API and finished formulation of Rosuvastatin in many Indian states like Himachal Pradesh, Andhra Pradesh, Tamil Nadu, Telangana, Kerala, Karnataka, Gujarat, Jammu & Kashmir, Chandigarh, Punjab, Uttarakhand, Chhattisgarh, Haryana, Maharashtra, Odisha, Uttar Pradesh, Delhi, Rajasthan, Madhya Pradesh, West Bengal, Bihar, Assam and many other Indian states.

     

    Niksan Pharmaceutical is also huge exporter of the API and finished formulations of Rosuvastatin in many Countries like Canada, Philippines, Trinidad & Tobago, Hungary, Nepal Australia, Lebanon, Sri Lanka, Finland, Pakistan, Puerto Rico, Bangladesh, United States, United Arab Emirates, Vietnam, Iraq,  South Korea, Nigeria, Jordan, Switzerland, Slovenia, 'Hong Kong, S.A.R., China', Malaysia, Saudi Arabia, United Kingdom, Israel, Sweden, Germany, Greece, Egypt, Czechia, Thailand, Indonesia, South Africa, Denmark, Romania and many other countries.

     

    Rosuvastatin belongs to a group of drugs "statins” which is used in diet of bad cholesterol and fats. It alsoincreases good cholesterol in the blood.

     

    SYNONYMS:  Rosuvastatin, Rosuvastatina

     

    IUPAC NAME:  (3R, 5S, 6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl) pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid

     

    CAS NO: 287714-41-4

     

    FORMULA: C22H28FN3O6S

     

    MOLECULAR MASS: 481.53 g/mol

     

    STORAGE OF Rosuvastatin:Store in cool and dry place.Keep medicine away from the reach of children and pets.Do not store this medicine in bathroom or any humidly place.

     

    APPLICATIONS OF Rosuvastatin:Rosuvastatin is used in diet of bad cholesterol and fats. It is also increase good cholesterol in the blood.

     

    HOW TO USE:Take one tablet in one day.You can take Rosuvastatin every day at any time.

    Take this medication with or without food.

     

    HOW Rosuvastatin WORKS:Rosuvastatin reducing the amount of cholesterol which made by liver. Which can helps you in good diet.

     

    CONTRAINDICATIONS: If you are a patient of liver problem or liver failure kindly avoid this medication.If you have a chronic kidney disease or metabolic syndrome x do not take this medication.Kindly avoid Rosuvastatin if you have recent operation and major traumatic injury.

     

    PHARMACOKINETICS OF Rosuvastatin: Approximately 20% Rosuvastatin absorbed after oral administration.Half life of Rosuvastatin is approximately 19 hours.Rosuvastatin is not widely metabolized.Maximum time of Peak plasma concentration of Rosuvastatin is 3 to 5 hours.Approximately 78% Rosuvastatin is excreted via bile and 28% excreted by renal excretion.

     

    SIDE EFFECTS OF Rosuvastatin:Many people use this drug but very few side effects are seen in the patient.In the rare case Rosuvastatin cause worsen diabetes.This drug may rarely cause muscle problem like muscle pain and weakness.

     

    PRECAUTION: During the pregnancy do not use Rosuvastatin it may harm and unborn baby.Consult with your doctor before the breast-feeding.Do not take alcohol and do not driving during the dose.Do not take this medication if you have any liver problem.

     

    CDSCO APPROVAL:Rosuvastatin Calcium eq. to Rosuvastatin 20mg/20mg + Fenofibrate BP 67.5mg/145mg Tablets are approved by CDSCO in India in 24.08.2011

    Rosuvastatin Calcium Tablet (Additional Indication) is approved by CDSCO in India in 24.05.2010

    Rosuvastatin Calcium IP eq to Rosuvastatin 5mg + Ezetimibe 10mg. (Additional Strength) is approved by CDSCO in India in 05.12.2011

    Rosuvastatin 5/10/20mg + Fenofibrate 67/145/160mg is approved by CDSCO in India in 23.08.2010

    Rosuvastatin Calcium tablets 5/10/20/40mg (Addl. Indication) is approved by CDSCO in India in 08.11.2008

    Rosuvastatin Calcium IP 5mg/10mg + Fenofibrate BP 160mg/160mg tablet is approved by CDSCO in India in 29.12.2010

    Rosuvastatin calcium tablet is approved by CDSCO in India in 2003

    Aspirin (EC Tablets) 75mg/75mg/150mg + Rosuvastatin (Granules) 5mg/10mg/10mg Capsules is approved by CDSCO in India in 30.03.2011

    Rosuvastatin Calcium Tablets 5/10/20mg (Additional Indication) is approved by CDSCO in India in 05.04.2011

     

    FORMULATIONS AVAILABLE IN MARKET:

    Rosuvastatin 10 MG tablets

    Rosuvastatin 20 MG tablets

    Rosuvastatin 40 MG tablets

    Rosuvastatin 5 MG tablets

    Rosuvastatin 30 MG tablets

    Rosuvastatin 15 MG tablets

    Rosuvastatin 10 MG+Aspirin 75 MG tablets

    Rosuvastatin 5 MG+Fenofibrate 67 MG tablets

    Rosuvastatin 10 MG+Fenofibrate 67 MG tablets

    Clopidogrel 75 MG +Rosuvastatin 10 MG tablets

    Fenofibrate 67 MG+Rosuvastatin 20 MG tablets

    Clopidogrel 75 MG+Rosuvastatin 20 MG tablets

    Aspirin 75 MG+Rosuvastatin 20 MG tablets

    Clopidogrel 75 MG+Rosuvastatin 5 MG tablets

    Rosuvastatin 10 MG+Ezetimibe 10 MG tablets

     

    Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

     

    REFERENCES:

     

    www.webmd.com

    https://pubchem.ncbi.nlm.nih.gov

    https://go.drugbank.com

    https://cdscoonline.gov.in

    https://www.wikipedia.org/

    https://www.drugs.com

    https://www.zaubacorp.com

    https://www.practo.com/consult

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