SUMATRIPTAN SUCCINATE

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:SUMATRIPTAN SUCCINATE
CAS No.:103628-46-2
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Company:NIKSAN PHARMACEUTICAL

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: ANKLESHWAR , GUJARAT , INDIA

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa

  • Monthly Production Capacity: 500 KG

    Packaging Information: HDPE DRUM WITH LDPE INNER LINNR

  • Delivery Lead Time: IMMEDIATE

    Sample Provided: yes

    Payment Terms: L/C

    Niksan Pharmaceutical is top leading manufacturer, supplier, exporter and trader of Sumatriptan in Indian states and also in world other countries. Sumatriptanis the best product of Niksan Pharmaceutical which exporting as a form of API and finished formulations.

     

    Our product Sumatriptan is world widely appreciated by our group companies and clients. We give best possible selling price of Sumatriptan to our clients, because customer satisfaction is our first priority.

     

    Niksan Pharmaceutical and Niksan group companies are the largest manufacturer, supplier and distributor of Sumatriptan API as well as Sumatriptan finished formulations provide in many Indian states like Kerala, Andhra Pradesh, Tamilnadu, Telangana, Karnataka, Punjab, Gujarat, Maharashtra, Delhi, Haryana, West Bengal, and Rajasthan, UP, Jammu and Kashmir and many others Indian states for many years.

     

    Niksan Pharmaceuticals are the largest exporter, supplier, and manufacturer of the Sumatriptan API and Sumatriptan finished formulations in many countries since many years like Nepal, UAE, Bangladesh, South Korea, Philippines, Australia, United Kingdom, United States, Estonia, Eswatini, Ethiopia, Fiji, Finland, France, Gabon, Gambia, Georgia, Liberia, Libya, Liechtenstein, Lithuania, Luxembourg, Malawi, Malaysia, Maldives, Mali, New Zealand, Nicaragua, Pakistan, Palau, Panama, South Africa, South Sudan, Spain and many other countries.

     

    Sumatriptan is belongs to drugs class called selective serotonin receptor agonists which is used to treatment of migraine and cluster headaches.

     

    SYNONYMS: Sumatriptan, Sumatriptán, Sumatriptanum

     

    IUPAC NAME:1-{3-[2-(dimethyl amino) ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide

     

    CAS NO: 103628-46-2

     

    FORMULA:C14H21N3O2S

     

    MOLECULAR MASS:295.4 g/mol

     

    STORAGE OF SUMATRIPTAN:  Keep Sumatriptan medicine in air tight container.Keep away from excess heat and moisture.Store it at room temperature.Keep all medication out of sight and reach of children. Do not store in bathroom and do not flush this medicine.

     

    APPLICATIONS OF SUMATRIPTAN: Sumatriptan used as a pain killer which helps to relive headache and pain.Sumatriptan is also use to treatment of migraine symptoms like vomiting, nausea and sensitivity to light or sound.

     

    HOW TO USE:Sumatriptan should take by mouth with or without food.Follow all directions on your prescription label or as your doctor recommends you.You can take Sumatriptan at first sign of a migraine headache.If the condition does not improve after taking Sumatriptan, you can take another tablet of Sumatriptan 2 hours after the 1st dose.

     

    HOW SUMATRIPTAN WORKS: It constricts the blood vessels in the head and reducing the signals of pain sent to the brain.Sumatriptan work on blood vessel in your brain and control stimulating serotonin receptors in the brain.

     

    CONTRAINDICATIONS:In your past history you have a heart attack or serotonin syndrome kindly avoid Sumatriptan medicine.Do not take this medicine if you have a problem of chest pain or Prinzmental angina.Kindly avoid Sumatriptan if you are a patient of high blood pressure and low supply of oxygen.Discuss with your doctor if you are an allergic to Sumatriptan.

     

    PHARMACOKINETICS OF SUMATRIPTAN:  Absorption of Sumatriptan in human body is weak after oral administration.

    Half-life of Sumatriptan is 2 hours as clinical pharmacology.

    Peak plasma concentration of Sumatriptan is 75% and usually reached within 45 min.

    Approximately 40% Sumatriptan excreted as feces and 22% excreted by urine.

     

    SIDE EFFECTS OF SUMATRIPTAN: Flushing, feelings of tingling, numbness, prickling, heat, tiredness, weakness, drowsiness, or dizziness are most common side effects are seen in patient.

    Sometimes this medicine may raise your blood pressure so check your blood pressure regularly during the dose of Sumatriptan.

    Sumatriptan cause bloody diarrhoea, trouble in speaking, sign of a stroke, shortness of breath.

    A very serious side effect to this drug is rare but get help your doctor if you are noticed any serious symptoms.

     

    PRECAUTIONS:  Check with your doctor if you take this medicine regularly and it did not work.

    Do not take Sumatriptan if you have used an MAO inhibitor.

    Discuss with your doctor before taking this medicine if you are a patient of heart dieses.

    Sumatriptan makes you dizzy so kindly avoid alcohol and do not drive vehicle. 

     

    CDSCO APPROVAL:  Sumatriptan 85 mg + Naproxen 500 mg Tablets are approved by CDSCO in India in 03.08.2009

    Sumatriptan tablets are approved by CDSCO in India in 06.02.1996

    Sumatriptan + Naproxen (50mg + 275mg) Tablets are approved by CDSCO in India in 24.11.2008

    Sumatriptan nasal spray are approved by CDSCO in India in 29.08.2001

     

    FORMULATIONS AVAILABLE IN MARKET:

    Sumatriptan tablets

    Sumatriptan 50 MG tablets

    Sumatriptan 25 MG tablets

    Sumatriptan 100 MG tablets

    Sumatriptan 20 MG tablets

    Sumatriptan 6 MG tablets

    Sumatriptan nasal spray

    Naproxen 550 MG+Sumatriptan 50 MG tablets

    Sumatriptan + Naproxen (50mg + 275mg) Tablets

    Sumatriptan 85 mg + Naproxen 500 mg Tablets

     

    Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

     

    REFERENCES:

     

    www.webmd.com

    https://pubchem.ncbi.nlm.nih.gov

    https://go.drugbank.com

    https://cdscoonline.gov.in

    https://www.wikipedia.org/

    https://www.drugs.com

    https://www.zaubacorp.com

    https://www.practo.com/consult

     

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