TENELIGLIPTIN

Niksan Pharmaceuticalis one of the leading manufacturer, supplier and exporter of the Teneligliptin. The best product manufactured by Niksan Pharmaceutical is Teneligliptin. We manufacture, supply and export best quality product of Teneligliptin API along withTeneligliptin formulations.

Niksan Pharmaceutical provides best quality product of Teneligliptinin all states of India like Kerala, Punjab, Rajasthan, Telangana, Bihar, Karnataka, Jammu and Kashmir, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Delhi, Tamil Nadu, Odisha, Madhya Pradesh, Andhra Pradesh, Haryana  and many other states.

Niksan Pharmaceutical is also manufacture and exports large quantity of Teneligliptin products in whole globe since many years in countries like Nepal, United Arab Emirates, South Korea, Philippines, Bangladesh, Australia, United States, United Kingdom, Bulgaria, Burkina Faso, Burundi, Estonia, Eswatini, Ethiopia, Mauritius, Mexico, Micronesia, Moldova, Monaco, Mongolia, Montenegro, Morocco, Mozambique, Myanmar (Burma), Namibia, Nauru, , Georgia, Germany, Ghana, Greece, Grenada, Guatemala, Guinea, Guinea-Bissau, Guyana, Haiti, Honduras, Hungary, Iceland, Indonesia, Iran, Iraq, Ireland, Israel, Italy, Jamaica, Japan and Jordan, Kazakhstan, Kenya, Kiribati, North Korea, South Korea, Kosovo, Kuwait, Kyrgyzstan, Laos, Latvia, Lebanon, Lesotho, Liberia, Libya, Liechtenstein, Lithuania, Luxembourg, Madagascar, Malawi, Malaysia, Maldives, Mali, Malta, Marshall Islands, Mauritania, Peru, Philippines, Poland, Portugal, Qatar, Romania, Russia, Rwanda, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines,Cabot Verde, Cambodia, Cameroon, Nepal, Netherlands, New Zealand, Nicaragua, Niger, Nigeria, North Macedonia, Norway, Oman, Pakistan, Palau, Panama, Papua New Guinea, Paraguay, Fiji, Finland, France, Gabon, The Gambia Canada, Central African Republic, Chad, Chile, China, Colombia, Comoros, Democratic Republic of the Congo, Republic of the Congo, Costa Rica, Cote d’Ivoire, Croatia, Cuba, Cyprus, Czech Republic, Denmark, Djibouti, Dominica, Dominican Republic, East Timor (Timor-Leste), Ecuador, Egypt, El Salvador, Equatorial Guinea, Eritrea, Samoa, San Marino, Sao Tome and Principe and Saudi Arabia and many other countries.

Teneligliptin is one type of anti-diabetic medication which is used in the treatment of type II diabetes mellitus. Teneligliptin is also called as DPP-4 inhibitors. Teneligliptin is given to the patient for control the risen blood sugar level.

SYNONYMS: Teneligliptin, DPP-4 inhibitor.

IUPAC NAME:1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazine

CAS NO: 760937-92-6

MOLECURAL FORMULA:C22H30N6OS

MOLAR MASS: 426.58 g/mol

STORAGE CONDITIONS:Store in room temperature away from direct heat and light.Do not put medication in humid place and in bathroom.

HOW TO USE:Take Teneligliptin tablet once a day with or without water.Also ask your doctor for advice if you have any confusion.

HOW TENELIGLIPTIN WORKS:Teneligliptin inhibits the DPP-4 which degrades the insulin in the body.By inhibiting the degradation of insulin, the glucose level in the body decreases and by this the Teneligliptin is used to control the rising blood glucose level.

PHARMACOKINETICS OF TENELIGLIPTIN:In the rats the oral absorption of Teneligliptin done very fast. Teneligliptin reaches the highest peak plasma concentration n 0.75-0.88hrs.The half-life o Teneligliptin is about 24.2hrs.About 65.6% of Teneligliptin metabolize and eliminated through hepatic and renal pathways and the remaining Teneligliptin is eliminates through kidney.

SIDE EFFECTS OF TENELIGLIPTIN:Generally the patient’s uses this medication does not have any serious side effects. But if you have some side effects like heart failure, join pain, skin blisters, weight gain, swelling of ankles, problem in breathing tell your doctor immediately. It Teneligliptin prescribed with other diabetic agents the blood glucose level can decrease which cause weakness, fainting, tiredness.

PRECAUTIONS: If you have disease related to heart, pancreas, kidney, liver tell your doctor before taking medication.Do not take alcohol while taking this medication it can cause low blood sugar level.Teneligliptin can cause blurred vision, sleepiness so don not operate any vehicle, and do not do any heavy lifting if you are not sure.

CDSCO APPROVAL: Teneligliptin Hydro bromide Hydrate 20mg approved by CDSCO in Indian in 18.05.2015.

FORMULATIONS AVAILABLE IN MARKET:

Teneligliptin 20mg tablets

Metformin 1000mg + Teneligliptin20mg tablets

Metformin 500mg+ Teneligliptin20mg tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

REFERENCES:

www.webmd.com

https://pubchem.ncbi.nlm.nih.gov

https://go.drugbank.com

https://cdscoonline.gov.in

https://www.wikipedia.org/

https://www.drugs.com

https://www.zaubacorp.com

https://www.practo.com/consult