Veterinary Drug Eprinomectin

Category:Intermediates > Pharmaceutical Intermediates
Product Name:Veterinary Drug Eprinomectin
CAS No.: 123997-26-2
Standard:In-house Standards
Price(USD):650.00
Company:Xi’an Lyphar Biotech Co., LTD

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Shaanxi

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia

  • Monthly Production Capacity: 800 Kilogram/Kilograms

    Packaging Information: 25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside

  • Delivery Lead Time: up to order

    Sample Provided: no

    Payment Terms: L/C, T/T,

    Veterinary Drug EprinomectinVeterinary-medicine1 basic info

     

    Product Name-----Eprinomectin------Batch No.---------------LY20170320

    Quantity--------------56.5 Kg--------------Production date------2017/03/20

    Expiry Date---------2019/03/09---------Test standard----------USP354

     

    Items

    Specifications

    Results

    Appearance

    White to yellowish crystalline powder

    Qualified

    Identification

    Infrared Absorption

    Qualified

    The retention times of the Component B1a peak and

    the Component B1b peak in the chromatogram of

    the Assay preparation correspond to those in the

    chromatogram of the standard preparation

    Qualified

    Specific rotation

    +132 °~ +140 °

    +137 °

    Water

    ≤2.0%

    0.3%

    Residue on ignition

    ≤0.1%

    0.1%

    Heavy metals

    ≤10ppm

    10ppm

    Residual

    solvents

    Acetonitrile ≤0.005%

    0.003%

    Sum of all solvent ≤0.5%

    0.2%

    8a-oxo-B1a

    ≤0.5%

    0.1%

    Related

    compounds

    Related compounds with relative retentions of

    0.23,0.93, and 1.16 correspond to B1a peak≤ 1.0%

    0.5%

    Related

    compounds

    Impurity A ≤1.0%

    0.2%

    Impurity E ≤ 1.0%

    0.1%

    All other known impurities ≤0.5%

    0.2%

    Total unknown impurities≤ 1.0%

    0.3%

    Total impurities ≤5.0%

    1.3%

    Assay

    Component B1a ≥90.0%

    93.1%

    Component B1a and Component B1b≥ 95.0%

    98.7%

    Conclusion

    The results conform with USP35

     6

     

    Eprinomectin is moderately used in ruminants, mainly in pour-ons and injectables. So far it is not used in swine, poultry or horses. Use in cats as a spot-on (in combination with other actives) is still rather scarce. So far it is not used in dogs.

    In most finished products, efficacy and safety depend not only on the amount of active ingredient(s) but also on their formulations (i.e. the type and amount of so-called inert ingredients), particularly in injectables and in topical pour-ons and spot-ons. These inert ingredients can significantly affect the pharmacokinetic behavior (e.g. absorption through the skin or from the injection site, distribution within the body, spreading throughout the body surface, etc.). Generic products usually contain the same amount of active ingredient(s) as the original product, but often in quite different formulations. In many cases, the curative (therapeutic) efficacy of the different formulations is quite comparable, but the protective (prophylactic) efficacy that determines the length of protection against re-infestations may be rather different.7

     

    Veteran.jpg

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