Liaoning Pharmaceutical Innovation Co., Ltd.
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CAS 599-79-1 Sulfasalazine
Product name |
Sulfasalazine |
CAS NO. |
599-79-1 |
Molecular Formula |
C18H14N4O5S |
EINECS: |
209-974-3 |
MW |
398.39 |
Appearance |
Dark yellow to brownish yellow powder |
Purity |
99% |
1. Sulfasalazine is an antiinflammatory agent that inhibits GSH-H-transferase. Sulfasalazine largely inhibits NF-κB activation and induces apoptosis in T-lymphocytes.
2. The compound also engages neutrophil apoptosis that can be abrogated by Tyr-K inhibitors, PKA inhibitors, or antioxidants. Sulfasalazine is shown to inhibit basic fibroblast growth factor-induced endothelial cell chemotaxis.
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