Niksan Pharmaceutical is among world’s top most manufacturer, supplier, exporter and trader of the Ambroxolfinished formulations moreover AmbroxolAPI. Niksan Pharmaceutical is the huge manufacturer, exporter and supplier of AmbroxolAPI and formulation situated in Ankleshwar, Gujarat, India. Niksan Pharmaceutical provides API and finished formulations of Ambroxol in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu, Madhya Pradesh, Uttar Pradesh, Kashmir Etc. Niksan Pharmaceutical is also large exporter of the API and finished pharmaceutical products of Ambroxol in many countries for years. The countries where we exporting are Mexico, Nicaragua, Indonesia, Guatemala, Honduras, Philippines, Dominican Republic, Panama, El Salvador, Hungary, Ecuador, Peru, Paraguay, Chile, Bolivia, Romania, Moldova, Venezuela, Costa Rica, Brazil, Lithuania, Germany, Vietnam, United Arab Emirates, Austria, Colombia, Bangladesh, Spain, 'Taiwan, China', 'Hong Kong, S.A.R., China', Argentina, Czechia, Singapore, Malaysia, Thailand, Portugal, Egypt, South Korea, Saudi Arabia, Switzerland, France, United States, Italy, Poland, Canada, United Kingdom, Japan and many more countries. Ambroxolis a mucolytic agent. Ambroxol removes the mucus from the airway by thing down the mucus and making it less sticky. Ambroxol used in the treatment of the respiratory disease associated with excessive mucous. SYNONYMS: Ambroxolum, Bisolvon metabolite vIII, Bromhexine metabolite vIII, Ambroxol IUPAC NAME :( 1r, 4r)-4-{[(2-amino-3, 5-dibromophenyl) methyl] amino} cyclohexan-1-ol CAS NO: 18683-91-5 FORMULA: C13H18Br2N2O MOLECULAR MASS: 378.10 g/mol STORAGE CONDITIONS:Store in cool and dry place.Do not place the container in humid place like bathroom or kitchen.Don’t put container open. Keep away from children and pets. HOW TO USE: Take 1-4 tablets in 2-3 divided doses.Give one teaspoon syrup to the 5 year old children 2-3 times a day.Take the medication regularly for the better result. HOW AMBROXOL WORKS: Ambroxol inhibits the guanylate cyclase. By this activity suppress the excessive secretion of mucous. Ambroxol also decrease the phlegm viscosity and makes it less stick. PHARMACOKINETICS: Almost all Ambroxol medication absorbed in body after the oral administration. This drug binds with almost 90% of blood plasma proteins.The half-life of the medicine is between 7-12 hours.The drug is metabolized in liver. About 90% of Ambroxol excreted by the urination SIDE EFFECTS: The most common side effect of Ambroxol is runny nose.The other side effects like GI irritation, abdominal problems.Tell your doctor if you see some side effects like skin rash, allergic reaction, itching, swelling of skin and breathing problem. PRECAUTIONS: Tell your doctor if you have allergic reactions to the Ambroxol.Take your doctor’s advice before giving the medication to children.If you see any side effects contact your doctor at early stage. CDSCO APPROVAL: Azithromycin 500mg + Ambroxol S.R (75mg) Tablet approved by CDSCO in India in 05.07.2007 Cetirizine 10 mg + Ambroxol 75 mg SR Tablet approved by CDSCO in India in13.04.2009 Gatifloxacin + Ambroxol tablets approved by CDSCO in India in24.12.2004 Levofloxacin (250mg/500mg) + Ambroxol SR 75mg tablet approved by CDSCO in India in08.02.2007 Desloratadine (2.5mg) + Ambroxol (30mg) + Guiphenasine (50mg) + Menthol 1mg/5ml Syrupapproved by CDSCO in India in02.03.2005 Ambroxol + loratadine + Guaifenesin Syrup (30mg + 5mg + 50mg per 5ml) approved by CDSCO in India in18.08.2008 Ambroxol 30 mg+ Terbutaline 2.5 mg + Guiphenasine 100mg + Menthol 2.5 mg per 5 ml syrup approved by CDSCO in India in27.10.2009 Ambroxol HCl + salbutamol + guaiphenesin + menthol approved by CDSCO in India in16.06.1999 Doxofylline 400 mg + Ambroxol 30 mg Tablets approved by CDSCO in India in23.12.2009 Gemifloxacin + Ambroxol (320mg + 75mg SR) FC Tablets approved by CDSCO in India in24.12.2008 Ambroxol tablet/liquid/drops approved by CDSCO in India in 01.12.1995 Ambroxol + Guaiphenesinapproved by CDSCO in India in 18.08.2000 Ambroxol + Guaiphenesin + Menthol + Pseudoephedrine approved by CDSCO in India in29.10.1999 Levocetirizine 5mg + Ambroxol Hydrochloride SR (75mg) tabletapproved by CDSCO in India in24.05.2006 Ambroxyl HCl SR+ Doxycycline HCl approved by CDSCO in India in 23.08.2001 FDC of Ambroxol + guaiphenesin approved by CDSCO in India in10.09.2001 FDC of Levocetirizine (5mg) + Ambroxol (75mg S.R) Capsule approved by CDSCO in India in29.07.2005 Olopatadine 5mg + Ambroxol 30mg tablets approved by CDSCO in India in05.03.2010 Ambroxol CR tabsapproved by CDSCO in India in 2002 Ambroxol + Pseudoephedrine + Chlorpheniramine maleate tabs/suspension/syrup approved by CDSCO in India in26.02.1998 Levocetrizine 2.5/5mg + Ambroxol 30mg/5ml of syrup approved by CDSCO in India in20.07.2006 Cetirizine 5/10mg + Ambroxol 30mg per 5ml syrup approved by CDSCO in India in23.02.2009 Ambroxol 30mg + Levosalbutamol 1mg + Guiphenesin 50mg /5ml syrup approved by CDSCO in India in19.03.2009 Ambroxol HCl. 15mg + Guiphenesin 50mg + Terbutaline sulphate 1.25mg + Menthol 2.5mg per 5 ml of syrupapproved by CDSCO in India in 26.03.2008 Ambroxol HCl 75mg (S.R) + Desloratadine 5mg Capsule approved by CDSCO in India in 11.11.2005 Levocetirizine 2 HCl 5mg+ Ambroxol HCl SR 75mg + Pseudoephedrine HCl 120mg SR Capsules approved by CDSCO in India in09.08.2006 Ambroxol HCl 30mg + Guaiphenesin 100mg + Terbutaline sulphate 2.5mg per 10ml Syrup approved by CDSCO in India in26.03.2008 FORMULATIONS AVAILABLE IN MARKET: Ambroxol HCl 30mg + Guaiphenesin 100mg + Terbutaline sulphate 2.5mg per 10ml Syrup Ambroxol HCl 75mg (S.R) + Desloratadine 5mg Capsules Levocetirizine 2 HCl 5mg+ Ambroxol HCl SR 75mg + Pseudoephedrine HCl 120mg SR Capsules Ambroxol HCl. 15mg + Guiphenesin 50mg + Terbutaline sulphate 1.25mg + Menthol 2.5mg per 5 ml of syrup Ambroxol 30mg + Levosalbutamol 1mg + Guiphenesin 50mg /5ml syrup Cetirizine 5/10mg + Ambroxol 30mg per 5ml syrup Levocetrizine 2.5/5mg + Ambroxol 30mg/5ml of syrup Ambroxol + Pseudoephedrine + Chlorpheniramine maleate tabs Ambroxol + Pseudoephedrine + Chlorpheniramine maleate syrup Ambroxol + Pseudoephedrine + Chlorpheniramine maleate suspension Ambroxol CR tablets Olopatadine 5mg + Ambroxol 30mg tablets FDC of Levocetirizine (5mg) + Ambroxol (75mg S.R) Capsule Ambroxyl HCl SR+ Doxycycline HCl tablets Levocetirizine 5mg + Ambroxol Hydrochloride SR (75mg) tablets Ambroxol + Guaiphenesin tablets Ambroxol tablets Ambroxol drops Ambroxol liquid Gemifloxacin + Ambroxol (320mg + 75mg SR) FC Tablets Doxofylline 400 mg + Ambroxol 30 mg Tablets Mbroxol 30 mg+ Terbutaline 2.5 mg + Guiphenasine 100mg + Menthol 2.5 mg per 5 ml syrup Desloratadine (2.5mg) + Ambroxol (30mg) + Guiphenasine (50mg) + Menthol 1mg/5ml Syrup Levofloxacin (250mg/500mg) + Ambroxol SR 75mg tablets Azithromycin 500mg + Ambroxol S.R (75mg) tablets Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk REFERENCES: |