The chemical name is 1,1,1,3,3,3-hexafluoro-2- (fluoromethoxy) propane, which is an organic compound with the chemical formula C4H3F7O. It is mainly used as an inhaled anesthetic and for general anesthesia
Basic information
Chemical formula: C4H3F7O
Molecular weight: 200.055
CAS number: 28523-86-6
Physical And Chemical Properties
Density: 1.505g/cm3
Boiling point: 58 ℃
Refractive index: 1.266
Steam pressure: 311mmHg at 25 ° C
Appearance: Colorless oily liquid
Solubility: Insoluble in water [1]
Sevoflurane Advantages
Sevoflurane is a colorless and transparent liquid that typically exerts its therapeutic effects in the form of volatile gases in clinical practice. Compared to traditional anesthetics, sevoflurane has many outstanding advantages as a gas anesthetic.
Its anesthesia induction time is shorter, the anesthesia takes effect faster, and the depth of anesthesia is easier to control. In addition, sevoflurane can be quickly excreted through normal breathing, and patients wake up quickly and smoothly, so the safety is also relatively high.
Product Performance
Inhalation of sevoflurane is indicated for the induction and maintenance of general anesthesia in adults and children, and is suitable for both hospitalized and outpatient patients.
Sevoflurane for inhalation is a halogenated systemic anesthetic, non flammable, non explosive, volatile liquid, used after vaporization.
Sevoflurane Application Scenarios
The characteristics of sevoflurane described in the requirements of International Electrotechnical Commission 601-2-13 are non flammable and non explosive.
Sevoflurane is a colorless and transparent liquid that does not contain additives or chemical stabilizers. It has no corrosive effect on stainless steel, brass, aluminum, nickel plated brass, chrome plated brass, and copper beryllium. Non irritating, it is miscible with ethanol, ether, chloroform, and benzene, and slightly soluble in water. Its samples can be stored stably under normal room lighting conditions as required.
Usage
Sevoflurane should be used by personnel trained in general anesthesia. Effective airway patency should be ensured, including artificial ventilators, oxygen delivery devices, and circulatory resuscitation equipment. Because the depth of anesthesia can be rapidly changed, only gasification devices that produce predictable concentrations of sevoflurane can be used.
Dosage And Administration
The concentration of sevoflurane delivered from the vaporizer during anesthesia should be determined, and a vaporizer specifically calibrated for sevoflurane should be used. The use of sevoflurane during general anesthesia should be individualized according to the patient's response. |
Pharma Sources Insight January 2025
