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Shandong Shengli Bioengineering
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(4R,5S,6S,7R,9R,11E,13E,15R,16R)-15-(((6-Deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxy)methyl)-6-((3,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-4-O-(3-methylbutanoyl)-alpha-L-ribo-hexopyranosyl)-3-(dimethylamino)-beta-D-glucopyranosyl)oxy)-16-ethyl-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-4-yl acetate(2R,3R)-2,3-dihydroxybutan edioate.
- Chemical abstract service (CAS) registry number: 63428-13-7
- Molecular formula:(C53H87NO19)2C4H6O6
- Relative molecular mass: 1192.3437
- Specification of Tylvalosin Tartrate
- Appearance: White or off-white powder
- pH: 3.0-5.0
- Composition: Tylvalosin A≥80%
- Potency: ≥800 u/mg (on dried basis)
- Shelf life: 2 years.
Tylvalosin (acetylisovaleryltylosin) tartrate, although a relatively new macrolide antibiotic, is currently successfully used in many countries of the world for the treatment and control of the major mycoplasmal infections such as chronic respiratory disease (CRD) and infectious synovitis in poultry.
Tylvalosin is up to 8 times more active in-vitro than tylosin against Mycoplasma gallisepticum & M.synoviae, is 3 times better absorbed, and also concentrates in target tissues. It is thus a powerful treatment for mycoplasmosis at a quarter the dose of tylosin. Furthermore Tylvalosin is effective against Mycoplasma strains resistant to tylosin and other macrolides.
Tylvalosin also shows strong activity against, Clostridium perfringens, the causal organism of Necrotic Enteritis in poultry. Now, in two new trials, it has shown extremely promising in vitro activity against Ornithobacterium rhinotracheale (ORT), an organism that is an important cause of respiratory disease in poultry.
- Content: 5%, 20%, 25%, 50%, 62.5%, 80%
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Pharma Sources Insight January 2025
