Cas no for 122111-03-9,Gemcitabine Hydrochloride ACID Cas number search msds database,online free cas number chemistry search engine,cas number sigma aldrich

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Home > CAS No. Inquiry > 122111-03-9

122111-03-9

[CAS Name] Gemcitabine Hydrochloride

[Formula] C9H12ClF2N3O4

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Basica Info

[CAS Name]Gemcitabine Hydrochloride
[Alias]2',2'-Difluoro-2'-deoxycytidine; 2,2-Difluoro-2-deoxycytidine DDFC; 4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1H-pyrimidin-2-one hydrochloride; Gemcitabine HCl; 4-amino-1-(2-deoxy-2,2-difluoropentofuranosyl)pyrimidin-2(1H)-one; 4-amino-1-(2-deoxy-2,2-difluoropentofuranosyl)pyrimidin-2(1H)-one hydrochloride (1:1); Gemcitabine hydrochlorid
[Number]122111-03-9
[EINECS]
[Formula]C9H12ClF2N3O4
[Molecular weight]299.6591

[Boiling point]482.7°C at 760 mmHg
[Density]2.41E-11mmHg at 25°C
[Flash point]245.7°C

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Luoxin Pharmaceutical Group Stock Co., Ltd.

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Wisdom Pharmaceutical Co.,Ltd.

antitumor drug

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Hangzhou Royall Import & Export Co.,Ltd

Appearance:

White crystalline granular, odorless

Molecular Weight:

299.66

Boiling Point:

482.7 °C at 760 mmHg

Melting Point:

>250°C dec

Flash Point:

245.7 °C

Solubility:

In water, 5.13X10+4 mg/L at 25 deg C (est)

Biological Activity:

Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. Displays antitumor activity in vitro and in vivo .

Usage:

An antineoplastic

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