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Home > CAS No. Inquiry > 144060-53-7

144060-53-7

[CAS Name] Febuxostat

[Formula] C16H16N2O3S

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Basica Info

[CAS Name]Febuxostat
[Alias]2-[3-Cyano-4-isobutoxyphenyl]-4-methylthiazole-5-carboxylic acid; 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid; 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid; Febuxostat (Polymorphs); 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
[Number]144060-53-7
[EINECS]
[Formula]C16H16N2O3S
[Molecular weight]316.3748

[Boiling point]536.6°C at 760 mmHg
[Density]2.41E-12mmHg at 25°C
[Flash point]278.3°C

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Beijing Mediking Biopharm Co., Ltd.	Factory Location:Beijing	Send Inquiry
Jiangsu Magic Biotechnology Co., Ltd	非布索坦化学性质熔点:238-239°(dec.)沸点:536.6±60.0°C(Predicted)密度:1.31±0.1g/cm3(Predicted)储存条件:2-8°C溶解度:DMSO(Slightly),Methanol(Slightly)酸度系数(pKa):2.48±0.10(Predicted)形态:powder颜色:WhitetoOff-WhiteMerck:14,3948InChI:InChI=1S/C16H16N2O3ChemicalbookS/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)InChIKey:BQSJTQLCZDPROO-UHFFFAOYSA-NSMILES:S1C(C(O)=O)=C(C)N=C1C1=CC=C(OCC(C)C)C(C#N)=C1CAS数据库:144060-53-7(CASDataBaseReference)	Send Inquiry
Shaanxi Xi Yue Pharmaceutical Co., LTD	Febuxostat is a selective xanthine oxidase inhibitor with the molecular formula C₁₆H₁₆N₂O₃S and CAS number 144060-53-7. It is primarily used to treat gout and hyperuricemia by inhibiting uric acid synthesis to reduce serum uric acid levels, making it suitable for long-term uric acid-lowering therapy. Its efficacy is superior to that of traditional drugs such as allopurinol, particularly offering greater safety for patients with impaired renal function. Common formulations include 40mg/80mg tablets, which must be used under medical supervision and may cause side effects such as liver function abnormalities. As a novel anti-gout medication, febuxostat is recommended as a first-line treatment option in guidelines from multiple countries.	Send Inquiry

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