Lomerizine hydrochloride was introduced as Teranas and Migsis in Japan for the treatment of migraine. It is the first in its class of dual sodium and calcium channel blockers to be marketed for this indication.In dogs, Lomerizine exerts a potent, selective and long-lasting vasodilation of cerebral arteries related to a combination of mechanisms, especially a functional block of L-type voltagesensitive calcium channels (L-VSCCs). Lomerizine increases cerebral blood flow compared to peripheral blood flow with only weak effects on systemic arterial blood pressure.
Product Name: High Quality Pitavastatin calcium Powder CAS 147526-32-7
CAS: 147526-32-7
MF: C25H26CaFNO4
MW: 463.56
EINECS:
Appearance: White Powder
Test Method: HPLC
Pitavastatin calcium is the calcium salt of pitavastatin. Used for treatment of hypercholesterolemia
(elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels
by diet and exercise. It has a role as an antioxidant. It is a calcium salt and a statin (synthetic).
Preserve in well-closed, light-resistant containers, and store in a refrigerator or freezer.
Pivastatin calcium is the first fully synthetic HMG-CoA reductase inhibitor jointly developed by Nissan Chemical
and Xingwa Co., LTD., a statin drug that reduces the liver's ability to produce cholesterol by inhibiting a liver
enzyme called HMGCo-A reductase, thereby improving elevated blood cholesterol levels. Mainly used to treat
patients with hypercholesterolemia and familial hypercholesterolemia, its lipid-lowering effect is very good, and
it is the most powerful lipid-lowering drug so far.
Items |
Specification |
Result |
Pitavastatin calcium |
98% |
98.5% |
Organoleptic |
|
|
Appearance |
white Powder |
Conforms |
Color |
Brown yellow powder |
Conforms |
Odor |
Characteristic |
Conforms |
Taste |
Characteristic |
Conforms |
Physical Characteristics |
|
|
Particle Size |
NLT 100% Through 80 mesh |
Conforms |
Loss on Drying |
<=12.0% |
Conforms |
Ash (Sulphated Ash) |
<=0.5% |
Conforms |
Total Heavy Metals |
≤10ppm |
Conforms |
Microbiological Tests |
|
|
Total Plate Count |
≤10000cfu/g |
Conforms |
Total Yeast & Mold |
≤1000cfu/g |
Conforms |
E.Coli |
Negative |
Negative |
Salmonella |
Negative |
Negative |
Staphylococcus |
Negative |
Negative |
|