SACUBITRIL+VALSARTAN

Chemical Name

LCZ-696(Sacubitril+Valsartan)

CAS Number

Molecular Formula

Molecular Weight

936623-90-4

2(C24H29N5O3).2(C24H29NO5).5(H2O).6Na

1922.06

Packing

As customer’s requirements

Storage

Store in a tightly sealed container away from heat and direct light, and in a cool dry place.

Usage

ITEMS

SPECIFICATION

Appearance

Off-white to white powder

Water    

Between 4.0% to 5.9%

Isomers

XST-A: ≤0.5%

LCZ-Q: ≤0.1%

LCZ-R: ≤0.1%

LCZ-S: ≤0.1%

Related Substances 

LCZ-A≤1.2%

Any unknown impurity:≤0.10%

Total impurities: ≤1.5%

Residue Solvents

Ethanol: ≤0.5%

Ethyl ester: ≤0.5%

Butanone≤0.5%

Acetone≤0.5%

Triethylamine: ≤0.032%

N-hexane: ≤0.029%

Assay

Valsartan 49.8%~52.4%

AHU377 47.1%~49.6%

LCZ696 97.0%~102.0%