June 05, 2025
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Citation: Gupta Banerjee, P., Paul, A., & Mukhopadhyay, M. (2024). Specialized manufacturing of calcium lactate gluconate (CLG) by West Bengal Chemical Industries Ltd (WBCIL): A comprehensive analytical perspective. Quest Journal of Research in Pharmaceutical Science, 10(2), 32–40. https://www.questjournals.com. https://questjournals.org/jrps/papers/vol10-issue7/10073240.pdf
Abstract: Calcium, the most prevalent mineral in the human body, is crucial for maintaining bone and dental health. Adequate calcium intake is essential, with the Indian Council of Medical Research recommending 600-800mg/dayfor adults and 1200 mg/day for pregnant and lactating women. Insufficient intake can lead to osteopenia and osteoporosis, making supplementation important. Among various forms, calcium lactate gluconate (CLG) standsout for its high solubility and bioavailability. This paper explores the synthesis, properties, and benefits of CLG, particularly a novel formulation by West Bengal Chemical Industries (WBCIL) where lactate and gluconate molecules are bonded to a single calcium ion, enhancing stability and absorption. WBCIL employs advanced analytical techniques such as FT-IR and NMR spectroscopy, alongside rigorous testing for heavy metals and microbial contaminants, ensuring the highest standards of safety and efficacy. The paper discusses the superior solubility, transparency, and stability of CLG, validating its suitability for pharmaceutical andindustrial applications. The findings underscore the importance of comprehensive analytical testing in guaranteeing the quality of CLG and highlight the pivotal role of advanced spectroscopic techniques inthedevelopment and qualitycontrol of chemical compounds.
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