Nicotinamide MonoNucleotide (NMN), the very promising Anti-Aging drug ingredient

By Bontac Bio-engineering

Bontac Bio-engineering (Shenzhen) Co., Ltd   is located in Shenzhen, China, professional in manufacturing enzyme cofactor and related product(e.g.: NAD,NADH,NADP, NADPH,PLP, Riboflavin 5 Phosphate, NMN. etc.).

Bontac is the first one in world to manufacture NMN (Nicotinamide Mononucleotide) in industrial scale.We manufacture NMN by enzymatic process, the manufacture process is green and environment friendly, the NMN we manufactured is with high purity and non-Poisonous substance residue.

What is NMN?

CAS No.：1094-61-7
Name：β-Nicotinamide Mononucleotide
Purity：≥98%
Appearance：White to yellowish powder
Application：Anti-aging supplements

Nicotinamide mononucleotide (NMN) is a naturally occurring compound in the body that plays a vital role in how cells use energy. It is involved in the synthesis of nicotinamide adenine dinucleotide (NAD), a coenzyme in cells that is essential for converting energy from nutrients into a form cells can use. NMN increases NAD which in turn activates a protein called SIRT1 to promote healthy metabolism throughout the body, particularly from the pancreas to the liver, and to muscles and fat tissue.

Why NMN is so popular?

NMN is getting quite a bit of buzz for its anti-aging potential. Nowadays, it seems like everyone’s on the hunt for an anti-aging miracle.

A recent study by Dr. David Sinclair, a genetics professor at Harvard, claims that aging can theoretically be reversed upon boosting production of an enzyme in cells. By increasing the production of nicotinamide adenine dinucleotide (NAD+), it can improve the number and performance of mitochondria, he says. And at this research demonstrated that short term supplementation with Nicotinamide mononucleotide (NMN) reversed many aspects of aging, making the cells of old mice resemble those of much younger mice, and greatly improving their health.

But beyond that, NADH, NR and NAD+ are now also considered the anti-aging breakthroughs of this century as researchers of leading institutes (like the Harvard Medical School) have declared that they are the only molecules known to mankind to reverse and not just delay aging. Are there any connections between them?

Pathway to Youth from NMN

How does NMN work? The mechanism of action of Nicotinamide MonoNucleotide is as shown in figure. NAD+ oxidized form of NAD, very important as a cofactor for health and longevity-related processes including DNA repair and mitochondrial operability. NADH reduced form of NAD. Acts as a biological reducing agent. 

NR, a precursor of NAD, and is a source of Vitamin B3.  Available as a commercial dietary supplement thought to promote NAD+.  One of the possible approaches to enhancing body levels of NAD+.

NMN, a precursor of NAD+ , and is a source of Vitamin B3. Both NR and NMN are NAD+ precursor, and able to increase the NAD+ level. The likely mechanism of NMN uptake is extracellular conversion to NR. In addition, NMN is more powerful than NR in its anti-aging effects.

Global NMN market

At present, global NMN market size is expected to grow steadily, owing to the growing demand for food and dietary supplements.

NMN market is segmented in four parts. Pharmaceuticals, medical supplies products, food and health supplements, cosmetics and others such as animal nutrition. Pharmaceuticals sector accounted for a notable share and is expected to grow during the forecast years due to the medicinal features of the product. Food and health supplements segment also had a significant share of the NMN market which is further expected to increase at a fast rate in the coming years owing to the increasing demand for high nutrition food and health products. Cosmetics user segment will likely experience growth due to rising cosmetics and personal care products industry. All in all, NMN is a promising product with great potentials.

Contact Bontac company at sales@bontac-bio.com