1L LC-MS grade Methanol

Test Items

Units

Specifications

Assay CH3OH(GC)

%

≥99.99

Density(20℃)

g/mL

0.791～0.793

Solubility with H2O

Pass test

Residue on evaporation

%

≤0.0001

Water

%

≤0.01

Acidity(as H+)

mmol/g

≤0.0002

Alkalinity(as OH-)

mmol/g

≤0.0001

Absorbance at 205 nm

Abs.Units

≤1.0

Absorbance at 210 nm

Abs.Units

≤0.45

Absorbance at 220 nm

Abs.Units

≤0.20

Absorbance at 230 nm

Abs.Units

≤0.10

Absorbance at 260 nm

Abs.Units

≤0.01

254nm Gradient Elution Test

mAU

≤2

235nm Gradient Elution Test

mAU

≤2

Fluorescence impurity at 254 nm

ppb

≤1.0

Fluorescence impurity at 365 nm

ppb

≤0.5

LC-MS(ESI+) as reserpine

ppb

≤50

LC-MS(ESI-) as 4-nitrophrnol

ppb

≤50

(K、Ag、Ba、Cd、Co、Cr、Cu、Mn、Ni、Pb、Sn)

ppb

≤5

Al、Ca、Mg、Fe

ppb

≤10

Na

ppb

≤100