98% up Boc-3-Hydroxy-1-Adamantyl-D-Glycine / Saxagliptin Intermediate 361442-00-4

Category:Intermediates > Pharmaceutical Intermediates
Product Name:98% up Boc-3-Hydroxy-1-Adamantyl-D-Glycine / Saxagliptin Intermediate 361442-00-4
CAS No.:361442-00-4
Standard:USP, BP, EP, JP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 1000kg

    Packaging Information: 1kg/bottle

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

     

    Product name

    Boc-3-Hydroxy-1-adamantyl-D-glycine / Saxagliptin intermediate

    CAS No.

    361442-00-4

    Molecular Formula

    C17H27NO5

    Molecular Weight

    325.405

    Quality Standard

    99% up by HPLC

    Appearance

    White to off-white powder

     

    COA of Boc-3-Hydroxy-1-adamantyl-D-glycine

     

    ITEMS

    SPECIFICATION

    RESULT

    Appearance

    White to off-white powder

    Conforms

    Identification by NMR/LC-MS HPLC

    The retention time of sample is concordant with reference standard

    Conforms

    Loss on drying

    ≤ 1.0%

    0.4%

    Purity(HPLC)

    ≥ 99.0%

    99.67%

    Conclusion

    The sample confirm to the enterprise standard

     

    Usage

     

    Boc-3-Hydroxy-1-adamantyl-D-glycine is one of key Intermediate of Saxagliptin.

     

    Physical properties about Boc-3-Hydroxy-1-adamantyl-D-glycine are:

    (1)ACD/LogP: 1.97;

    (2)# of Rule of 5 Violations: 0 ;

    (3)#H bond acceptors: 6;

    (4)#H bond donors: 3;

    (5)#Freely Rotating Bonds: 6;

    (6)Polar Surface Area: 95.86 Å2;

    (7)Index of Refraction: 1.575;

    (8)Molar Refractivity: 82.911 cm3;

    (9)Molar Volume: 251.06 cm3;

    (10)Polarizability: 32.868 ×10-24cm3;

    (11)Surface Tension: 59.817 dyne/cm;

    (12)Density: 1.296 g/cm3;

    (13)Flash Point: 254.53 °C;

    (14)Enthalpy of Vaporization: 88.13 kJ/mol;

    (15)Boiling Point: 497.253 °C at 760 mmHg;

    (16)Vapour Pressure: 0 mmHg at 25°C.

     

    We have a professional team specialized in custom developing & manufacturing pharmaceutical intermediates or APIs.

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