99.5% up R-(+)-Lipoic Acid Sodium Salt 176110-81-9

Category:Natural Extracts > Food & Beverage Raw Materials
Product Name:99.5% up R-(+)-Lipoic Acid Sodium Salt 176110-81-9
CAS No.:176110-81-9
Standard:In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co. Ltd

Basic Info
  • Grade: Food Grade

    Factory Location: Xiamen

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 1000kg/month

    Contract Manufacturing: CMO

    Packaging Information: 25kg/drum

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/C

    Product Information

     

    Product name

    R-(+)-Lipoic Acid Sodium Salt

    R-(+)-Lipoic Acid Sodium

    R+ALA sodium salt;

    R+ALA sodium

    CAS No.

    176110-81-9

    Molecular Formula

    C8H13NaO2S2

    Molecular Weight

    228.31

    Quality Standard

    R-(+)-Lipoic Acid Sodium  99.0% by HPLC;

    R-Alpha Lipoic Acid≥ 80.0% by HPLC

    Appearance

    Off-white to light-yellow powder

     

    COA

     

    Test Items

    Specifications

    Results

    Appearance

    Off-white to light-yellow powder

    Conforms

    Melting point

    230-250°C

    Conforms

    Solubility(H2O)

    Soluble in water

    Conforms

    Specific rotation

    +85°  +105°

    +95.3°

    Loss on drying

     3.0%

    0.8%

    Heavy metals

     10 ppm

    <10 ppm

    Total plate count

     1000 cfu/g

    <10 cfu/g

    Moulds and yeasts

     100 cfu/g

    <10 cfu/g

    Escherichia coli

    Negative/g

    Negative

    Salmonella

    Negative/10g

    Negative

    Particle size

    100% through 20 mesh

    80% through 80 mesh

    Conforms

    Assay:

    R-alpha lipoic acid

     80%(External standard)

    82.5%

    Assay:

    R-(+)-lipoic acid sodium

     99.0% (Area Normalization)

    99.8%

    Conclusion

    Complies with Enterprise standard

     

     

    Usage

     

    Core Functions of R-(+)-Lipoic Acid Sodium

    1. Potent Antioxidant Activity: As the natural R-enantiomer, it directly participates in mitochondrial energy metabolism, scavenges free radicals, and regenerates other antioxidants (e.g., vitamins C/E, glutathione).

    2. Metabolic Regulation: Enhances insulin sensitivity, supporting the management of diabetic neuropathy and metabolic syndrome.

    3. Neuroprotection: Crosses the blood-brain barrier to inhibit neuroinflammation and delay cognitive decline (e.g., applications in Alzheimers research).

    4. Anti-Aging & Skin Health:Inhibits AGEs (advanced glycation end products) and reduces UV-induced skin damage.

    5. Bioavailability Superiority: Compared to racemic (D/L) lipoic acid, the R-form achieves 40-50% higher oral absorption and 30% faster peak plasma concentration.

     

    Competitive Advantages of SinowayR-ALA sodium:

    1. Cost Efficiency: Localized raw material procurement (e.g., adipic acid, sulfur sources) and continuous flow process optimization enable 20-30% reduction in production costs.

    2. Sustainable Production: Utilizes immobilized catalysts and solvent recovery systems to minimize organic waste (compliant with REACH/EPA standards).

    Synthesis Breakthroughs: Asymmetric synthesis (e.g., enzymatic resolution) achieves 99.5% R-enantiomer purity with <0.1% chiral impurities.

     

    Applications of R+Lipoic Acid Sodium

    1. Pharmaceuticals: Injectable formulations for diabetic neuropathy, oral sustained-release tablets.

    2. Nutraceuticals: High-absorption antioxidant capsules (combined with CoQ10, NAC).

    Cosmeceuticals: Photoaging serums (pH-stable formulas at 5.56.5).


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