99% up by HPLC EDMF Febuxostat 144060-53-7

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:99% up by HPLC EDMF Febuxostat 144060-53-7
CAS No.:144060-53-7
Standard:USP, BP, EP, JP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 1000kg

    Packaging Information: 25kg/drum 1kg/bottle

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Febuxostat

    CAS No.

    144060-53-7

    Molecular Formula

    C16H16N2O3S

    Molecular Weight

    316.3748

    Quality Standard

    99% up by HPLC, EDMF

    Appearance

    White powder

     

    COA of Febuxostat

     

    ITEMS

    SPECIFICATIONS

    RESULTS

    CHARACTERISTICS

    A WHITE OR WHITE CRYSTALLINE POWDER

    COMPLIES

    IDENTIFICATION

    POSITIVE

    COMPLIES

    SOLUBILITY OF SOLUTION 

    AND COLOUR

    COMPLIES

    COMPLIES

    ASSAY(BY HPLC)

    98%~102%

    99.7%

    RELATED IMPURITIES

    NMT0.1%

    0.1%

    LOSS ON DRYING

    NMT0.5%

    0.2%

    RESIDUE ON IGNITION

    NMT0.2%

    0.05%

    HEAVY METALS

    NMT0.001%

    NMT0.001%

    CONCLUSION:THE PRODUCT COMPLIES WITH EDMF STANDARD.

     

    Usage

     

    Function of Febuxostat
     

    The main effect of febuxostat is to promote uric acid excretion and inhibit uric acid production.

     

    At present, the drugs for the treatment of elevated uric acid in my country mainly include two categories: 1. Drugs that promote the excretion of uric acid, such as benzbromarone; 2. Drugs that inhibit the production of uric acid, the most representative of which is allopurinol. Febuxostat is a new type of uric acid-lowering drug with a similar mechanism of action to allopurinol, mainly inhibiting xanthinase, thereby inhibiting the production of uric acid. At the same time, febuxostat has less side effects and has less impact on liver and kidney function, especially patients with moderate or lower renal insufficiency can use febuxostat with confidence. At the same time, patients can achieve a good therapeutic effect on gout by cooperating with diet and strict low-purine diet.

     

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