99% up by HPLC, GMP, JP Pitavastatin Calcium 147526-32-7

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:99% up by HPLC, GMP, JP Pitavastatin Calcium 147526-32-7
CAS No.:147526-32-7
Standard:USP, BP, EP, JP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co., Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 1000kg

    Packaging Information: 25kg/drum 1kg/bottle

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Pitavastatin Calcium

    CAS No.

    147526-32-7

    Molecular Formula

    (C25H23FNO4)2.Ca

    Molecular Weight

    880.98

    Quality Standard

    99% up by HPLC, GMP,JP

    Appearance

    White or pale yellow powder

     

    COA of Pitavastatin calcium

     

    ITEMS

    SPECIFICATION

    RESULT

    Appearance

    White or pale yellow powder

    Conforms

    Solubility

    Slightly soluble in methanol, very slightly soluble in water and ethannol. It dissolves in dilute hydrochloric acid.

    Conforms

    Specific optical rotation

    +22.0。~ +24.50。

    +23.6。

     

    Identity

    Chemical reaction: Positive

    Positive

    UV: Should conform to reference spectrum

    Conforms

    IR: Should conform to standard

    Conforms

     

     

    Related substance

    Any individual impurity ≤ 0.1%

    Enantiomer of Pitavastatin ≤ 0.1%

    RRT1.1 ≤ 0.5%

    Total impurity ≤ 1.5%

    0.08%

    Undetected

    0.15%

    0.4%

    Heavy metals

     ≤ 20ppm

    Conforms

    Water

    9.0%-13.0%

    10.0%

    Assay

    98.0~102.0%(anhydrous substance )

    101.0%

    Conclusion

    The results above meet all requirements under JP16

     

    Usage

    Function of Pitavastatin calcium

    Pitavastatin calcium is a statin drug. It inhibits cholesterol synthesis. By inhibiting cholesterol synthesis, it reduces the content of low-density lipoprotein cholesterol and total cholesterol in plasma, so it is a lipid-lowering drug.

     

    Who is pitavastatin used for?

     

    1. People have imple hypercholesterolemia, with relatively high blood lipid levels, requires treatment to reduce low-density lipoprotein cholesterol, and the drug can be stopped after the blood lipids drop.

     

    2. People with some manifestations of atherosclerosis, such as those who can see obvious plaques on carotid ultrasound, and whose blood lipid levels need to be controlled to a lower level.

     

    3. People with coronary heart disease or cerebral atherosclerosis, or very obvious peripheral atherosclerosis, he has atherosclerotic cardiovascular and cerebrovascular disease, he must take statin for life, pitavastatin can be used for a long time . It mostly brings it down to the guideline-recommended value for LDL cholesterol, not the value for LDL cholesterol on the test sheet.

     

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