99% up by HPLC, GMP Penciclovir 39809-25-1

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:99% up by HPLC, GMP Penciclovir 39809-25-1
CAS No.:39809-25-1
Standard:USP, BP, EP, JP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 1000kg

    Packaging Information: 25kg/drum 1kg/bottle

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Penciclovir

    CAS No.

    39809-25-1

    Molecular Formula

    C10H15N5O3

    Molecular Weight

    253.117

    Quality Standard

    99% up, GMP

    Appearance

    White or pale yellow powder

     

    COA of Penciciovir

     

    ITEMS

    SPECIFICATIONS

    RESULTS

    Appearance

    White or pale yellow crystalline powder

     Complies

    PH

    5.5 to 7.5

     6.5

    Chloride

    Not more than 0.015%

    Complies

    Related substances

    Total impurities

     

    Not more than 1.0%

    Complies

    Loss on drying

    Not more than 0.5%

    Complies

    Residue on ignition

    Not more than 0.1%

    Complies

    Heavy metals

    Not more than 0.002%

    Complies

    Assay

    Not less than 99.0%,calculated on dried basis

    99.6%

    Conclusion

    Complies with the specification

     

    Usage

     

    Function of Penciciovir

    Penciclovir is a nucleoside antiviral drug, which has inhibitory effect on type I and type II herpes simplex virus in vitro. In virus-infected cells, viral thymidine kinase phosphorylates penciclovir to penciclovir monophosphate, and cell kinase converts penciclovir monophosphate to penciclovir triphosphate. In vitro experiments show that penciclovir triphosphate and deoxyguanosine triphosphate competitively inhibit herpes simplex virus polymerase, thereby selectively inhibiting herpes simplex virus DNA synthesis and inhibition. Therefore, penciclovir is suitable for the treatment of a variety of herpes virus infections. It has the characteristics of low toxicity and high virus sensitivity. Penciclovir has low oral absorption and is often used for topical administration. Famciclovir is a prodrug of penciclovir and is well absorbed orally.

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