Apalutamide

Product Details
Product name: Apalutamide

Alias: 4-[7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methylbenzoyl;apalutamide;Apalutamide is a 2nd-generation nonsteroidal androgen receptor inhibitory drug used in the treatment of nonmetastatic desmoplastic resistant prostate cancer. Apalutamide; Apalutamide; Apalutamide//Apalutamide; ARN-509, Apalutamide; Lactatinib Impurity

English name: Apalutamide

English Synonyms: ARN-509; 4-(7-(6-cyano-5-(trifluoroMethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspirooctan-5-yl)-2-fluoro-N-MethylbenzaMide; ARN509; Benzamide; Apalutamide; Apalutamide impurity AR509;Benzamide,4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]oct-5-yl]-2-fluoro-N-methyl-; 4-[7 -[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamideARN-509. AR509100G;4-[7-[6-Cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide. ARV-509

CAS No.: 956104-40-8

Molecular Formula: C21H15F4N5O2S

Molecular weight: 477.43

EINECS No.: 807-449-9

Properties: white powder

Density: 1.59±0.1g/cm3(Predicted)

Storage condition: Storeat-20°C

Solubility: ≥23.85mChemicalbookg/mL in DMSO; insoluble in water; ≥7.33mg/mL in ethanol

Form: solid

Acidity coefficient: (pKa)13.83±0.46(Predicted)

Use: Used as pharmaceutical intermediates for anti-ED drugs.

Product specification: 1kg/barrel, 2kg/barrel, 5kg/barrel, 10kg/barrel, 15kg/barrel, 20kg/barrel, 25kg/barrel, etc., and can be separately subcontracted according to customers' requirements.

Price: Price is for reference only, call us for one-to-one quotation.

Apalutamide Upstream and downstream product information
Upstream raw material: 5-isothiocyanoyl-3-(trifluoromethyl)pyridine-2-cyano 4-[(1-cyanocyclobutyl)amino]-N-methylbenzamide

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